[HTML][HTML] A review of the clinical efficacy of FDA-approved antibody‒drug conjugates in human cancers
K Liu, M Li, Y Li, Y Li, Z Chen, Y Tang, M Yang… - Molecular Cancer, 2024 - Springer
While strategies such as chemotherapy and immunotherapy have become the first-line
standard therapies for patients with advanced or metastatic cancer, acquired resistance is …
standard therapies for patients with advanced or metastatic cancer, acquired resistance is …
[HTML][HTML] Package delivered: folate receptor-mediated transporters in cancer therapy and diagnosis
Neoplasias pose a significant threat to aging society, underscoring the urgent need to
overcome the limitations of traditional chemotherapy through pioneering strategies …
overcome the limitations of traditional chemotherapy through pioneering strategies …
Immunoantitumor Activity and Oxygenation Effect Based on Iron–Copper-Doped Folic Acid Carbon Dots
S Li, H Zhang, Y Bao, H Zhang, J Wang… - … Applied Materials & …, 2024 - ACS Publications
Cancer metastasis and recurrence are closely associated with immunosuppression and a
hypoxic tumor microenvironment. Chemodynamic therapy (CDT) and photothermodynamic …
hypoxic tumor microenvironment. Chemodynamic therapy (CDT) and photothermodynamic …
[HTML][HTML] Folate receptor overexpression induces toxicity in a diet-dependent manner in C. elegans
B Shrestha, M Tallila, O Matilainen - Scientific Reports, 2024 - nature.com
Folate receptor (FR) alpha (FOLR1) and beta (FOLR2) are membrane-anchored folate
transporters that are expressed at low levels in normal tissues, while their expression is …
transporters that are expressed at low levels in normal tissues, while their expression is …
Construction of tumor-cell nucleus targeting lanthanide nano-prodrugs with lutetium-177 labelling for high-efficient tumor fluorescence-localization and radionuclide …
Z Wu, H Chen, H Zhang, L Ye, J Ke, Y Liu, P Sun… - Nano Today, 2024 - Elsevier
Tumor-cell nucleus targeting is highly desired for theragnostic nano-prodrugs (NPDs) to
enhance cancer diagnostic and therapeutic efficacy as compared to those targeting the …
enhance cancer diagnostic and therapeutic efficacy as compared to those targeting the …
Sensitivity and specificity of folate receptor α-positive circulating tumour cells in gastric cancer
B Cao, L Liu, R Zhang, H Dong… - Postgraduate Medical …, 2024 - academic.oup.com
Purpose We aimed to investigate whether folate receptor α (FRα)-positive circulating tumour
cells (CTCs) could be used as a noninvasive liquid biopsy approach in gastric cancer (GC) …
cells (CTCs) could be used as a noninvasive liquid biopsy approach in gastric cancer (GC) …
Preparation of novel sulfated polysaccharide-carboxymethyl-5-fluorouracil-folic acid conjugates for targeted anticancer drug delivery
N Ma, R Li, SG You, DJ Zhang - International Journal of Biological …, 2024 - Elsevier
GFP 1, a sulfated polysaccharide extracted from Grateloupia filicina, exhibits remarkable
immunomodulatory activity. To reduce the side effects of 5-fluorouracil (5-FU), GFP 1 was …
immunomodulatory activity. To reduce the side effects of 5-fluorouracil (5-FU), GFP 1 was …
New hopes and promises in the treatment of ovarian cancer focusing on targeted treatment—a narrative review
M Satora, K Kułak, B Zaremba, A Grunwald… - Frontiers in …, 2024 - frontiersin.org
Unfortunately, ovarian cancer is still diagnosed most often only in an advanced stage and is
also the most lethal gynecological cancer. Another problem is the fact that treated patients …
also the most lethal gynecological cancer. Another problem is the fact that treated patients …
Tris-assisted one-step fabrication of functional carbon dots for specific folate receptor positive-expressed cancer cell imaging
L Tong, X Wang, X Zhang, C Xu, M Qiao, Z Chen… - Talanta, 2024 - Elsevier
Specific staining of cancer cells is momentous for cancer research. Nanoprobe with
multivalent recognition is emerging as powerful tools for bioimaging, but the nonspecific cell …
multivalent recognition is emerging as powerful tools for bioimaging, but the nonspecific cell …
[HTML][HTML] Blood FOLR3 methylation dysregulations and heterogeneity in non-small lung cancer highlight its strong associations with lung squamous carcinoma
Y Qu, X Zhang, R Qiao, F Di, Y Song, J Wang, L Ji… - Respiratory …, 2024 - Springer
Background Non-small cell lung cancer (NSCLC) accounts for the vast majority of lung
cancers. Early detection is crucial to reduce lung cancer-related mortality. Aberrant DNA …
cancers. Early detection is crucial to reduce lung cancer-related mortality. Aberrant DNA …