[HTML][HTML] Indolent cancer and pattern of progression: Two missing parameters in trial design for hepatology

M Iavarone, JC Nault, G Cabibbo, F Torres, M Reig - Hepatology, 2024 - journals.lww.com
The indolent and aggressive behaviors of HCC might have a role in clinical trial (CT) results;
however, the indolent HCC is less analyzed compared to others cancer. Indolent profile …

Portal hypertension and variceal bleeding in patients with liver cancer: evidence gaps for prevention and management

M Allaire, D Thabut - Hepatology, 2024 - journals.lww.com
Results: Recent therapeutic advances observed in the management of HCC, notably
through the advent of immunotherapy, have led to a clear improvement in the survival of …

[HTML][HTML] Machine learning-based clinical decision support system for treatment recommendation and overall survival prediction of hepatocellular carcinoma: a multi …

KH Lee, GH Choi, J Yun, J Choi, MJ Goh, DH Sinn… - npj Digital …, 2024 - nature.com
The treatment decisions for patients with hepatocellular carcinoma are determined by a wide
range of factors, and there is a significant difference between the recommendations of …

Incidence and predictors of hepatocellular carcinoma in patients with autoimmune hepatitis

F Colapietro, P Maisonneuve, E Lytvyak, U Beuers… - Journal of …, 2024 - Elsevier
Background and Aims Autoimmune hepatitis (AIH) is a rare chronic liver disease of unknown
aetiology; the risk of hepatocellular carcinoma (HCC) remains unclear and risk factors are …

ACG clinical guideline: alcohol-associated liver disease

LL Jophlin, AK Singal, R Bataller… - Official journal of the …, 2024 - journals.lww.com
Alcohol-associated liver disease (ALD) is the most common cause of advanced hepatic
disease and frequent indication for liver transplantation worldwide. With harmful alcohol use …

Antiviral Therapy Utilization and 10-Year Outcomes in Resected Hepatitis B Virus–and Hepatitis C Virus–Related Hepatocellular Carcinoma

DQ Huang, JK Hoang, R Kamal, PC Tsai… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE There are limited data on antiviral treatment utilization and its impact on long-
term outcomes of hepatitis B virus (HBV)–and hepatitis C virus (HCV)–related hepatocellular …

[HTML][HTML] Long-term outcome of adjuvant radiotherapy upon postoperative relapse of centrally located hepatocellular carcinoma: a real-world study

C Tao, N Hu, Y Liu, H Wang, Z Wang, K Zhang… - Scientific Reports, 2024 - nature.com
Despite that surgical resection is widely regarded as the most effective approach to the
treatment of liver cancer, its safety and efficacy upon centrally located hepatocellular …

2023 update of Indian national association for study of the liver consensus on management of intermediate and advanced hepatocellular carcinoma: the Puri III …

A Kumar, SK Acharya, SP Singh, A Duseja… - Journal of Clinical and …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) presents significant treatment challenges despite
considerable advancements in its management. The Indian National Association for the …

RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion

Q Zhuang, Z Dai, X Xu, S Bai, Y Zhang, Y Zheng… - Cancer Research, 2024 - AACR
Immunotherapies such as immune checkpoint blockade have achieved remarkable success
in treating cancer. Unfortunately, response rates have been limited in multiple cancers …

[HTML][HTML] A meta-analysis and real-world cohort study on the sex-related differences in efficacy and safety of immunotherapy for hepatocellular carcinoma

L Balcar, B Scheiner, CAM Fulgenzi, A D'Alessio… - JHEP reports, 2024 - Elsevier
Background & Aims Sex-related differences in the immune pathogenesis of hepatocellular
carcinoma (HCC), particularly related to oestrogen-dependent secretion of pro-tumourigenic …