Probiotics with diverse and crucial properties and functions have attracted broad interest
from many researchers, who adopt intestinal delivery of probiotics to modulate the gut …

Recent advances in engineered bacterial therapeutics underscore their potential in treating
diseases via targeted, live interventions. Despite their promising performance in early …

Probiotic-based therapies have shown great potential in the prevention and treatment of
many diseases by positively regulating intestinal flora homeostasis. However, the efficacy of …

Probiotic and engineered microbe-based therapeutics are an emerging class of
pharmaceutical agents. They represent a promising strategy for treating various chronic and …

Lactobacilli are ubiquitous in nature and symbiotically provide health benefits for countless
organisms including humans, animals and plants. They are vital for the fermented food …

This review examines the complex connection between commensal microbiota and the
development of opportunistic infections. Several underlying conditions, such as metabolic …

Live biotherapeutic product (LBP), a type of biological product, holds promise for the
prevention or treatment of metabolic disease and pathogenic infection. Probiotics are live …

Intrinsic characteristics of microorganisms, including non‐specific metabolism sites, toxic
byproducts and uncontrolled proliferation constrain their exploitation in medical applications …

Highlights•Next-generation probiotics can be used as promising live biotherapeutics.•Many
beneficial effects are attributed to prebiotics.•New forms of administration such as consortia …

The genus Bacteroides, a predominant group in the human gut microbiome, presents
significant potential for microbiome engineering and the development of live biotherapeutics …