[HTML][HTML] Platelets: Orchestrators of immunity in host defense and beyond

L Nicolai, K Pekayvaz, S Massberg - Immunity, 2024 - cell.com
Platelets prevent blood loss during vascular injury and contribute to thrombus formation in
cardiovascular disease. Beyond these classical roles, platelets are critical for the host …

Fibroblasts and platelets: a face-to-face dialogue at the heart of cardiac fibrosis

C Dufeys, J Bodart, L Bertrand… - American Journal of …, 2024 - journals.physiology.org
Myocardial fibrosis is a feature found in most cardiac diseases and a key element
contributing to heart failure and its progression. It has therefore become a subject of …

Evidence That Anemia Accelerates AS Progression Via Shear-Induced TGF-β1 Activation: Heyde's Syndrome Comes Full Circle

K Subramani, J Bander, S Chen… - Basic to Translational …, 2024 - jacc.org
The severity of aortic stenosis (AS) is associated with acquired von Willebrand syndrome
(AVWS) and gastrointestinal bleeding, leading to anemia (Heyde's syndrome). We …

[HTML][HTML] Characterization of Biomarkers of Thrombo-Inflammation in Patients with First-Diagnosed Atrial Fibrillation

J Friebel, M Wegner, L Blöbaum, PA Schencke… - International Journal of …, 2024 - mdpi.com
Patients with first-diagnosed atrial fibrillation (FDAF) exhibit major adverse cardiovascular
events (MACEs) during follow-up. Preclinical models have demonstrated that thrombo …

[HTML][HTML] Platelet lipidomics and de novo lipogenesis: impact on health and disease

L Pirotton, E de Cartier d'Yves, L Bertrand… - Current Opinion in …, 2024 - journals.lww.com
Platelet lipidomics and de novo lipogenesis: impact on healt... : Current Opinion in
Hematology Platelet lipidomics and de novo lipogenesis: impact on health and disease …

Platelets and extracellular vesicles in disease promotion via cellular cross-talk and eicosanoid biosynthesis

A Contursi, S Tacconelli, S Di Berardino… - Prostaglandins & Other …, 2024 - Elsevier
New insights have been gained on the role of platelets beyond thrombosis. Platelets can
accumulate in damaged and inflamed tissues, acting as a sentinel to detect and repair tissue …

Platelet-Derived TGF-β1 Promotes Deep Vein Thrombosis

S Zhang, Y Li, J Zhang, Y Sun, X Chu… - Thrombosis and …, 2024 - thieme-connect.com
Background Transforming growth factor-β1 (TGF-β1) modulates multiple cellular functions
during development and tissue homeostasis. A large amount of TGF-β1 is stored in platelet …

[HTML][HTML] Distinct phenotypes induced by acute hypoxia and TGF-β1 in human adult cardiac fibroblasts

NN Khalil, ML Rexius-Hall, S Escopete… - Journal of Molecular and …, 2024 - Elsevier
Myocardial infarction (MI) causes hypoxic injury to downstream myocardial tissue, which
initiates a wound healing response that replaces injured myocardial tissue with a scar …

[PDF][PDF] 原发性干燥综合征继发免疫性血小板减少症的临床特点及危险因素分析

王丽丽, 黄鸿影, 王信, 赵韵琦, 陈琳洁 - 蚌埠医学院学报, 2024 - xuebao.bbmu.edu.cn
原发性干燥综合征继发免疫性血小板减少症的临床特点及危险因素分析王丽丽,黄鸿影,王信,赵
韵 Page 1 原发性干燥综合征继发免疫性血小板减少症的临床特点及危险因素分析 王丽丽,黄鸿影 …

Der Einfluss thrombozytärer microRNAs auf die myokardiale Inflammation und das ventrikuläre Remodeling nach Ischämie und Reperfusion am Herzen

JP Schütte - 2024 - tobias-lib.ub.uni-tuebingen.de
Die koronare Herzerkrankung (KHK) und darunter ihre schwerwiegendste Komplikation, der
akute Myokardinfarkt, stellen heute die häufigste Todesursache weltweit dar. Insgesamt sind …