AIM The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial
Fibrillation” provides recommendations to guide clinicians in the treatment of patients with …

Atrial myopathy is a condition that consists of electrical, structural, contractile, and autonomic
remodeling of the atria and is the substrate for development of atrial fibrillation, the most …

Cardiovascular diseases are the most common cause of worldwide morbidity and mortality,
highlighting the necessity for advanced therapeutic strategies. Ca2+/calmodulin-dependent …

BACKGROUND: G protein–coupled receptors play a critical role in atrial fibrillation (AF).
Spexin is a novel ligand of galanin receptors (GALRs). In this study, we investigated the …

Diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF). The
mechanisms underlying DM-associated AF are unclear. AF and DM are both related to …

Atrial fibrillation (AFib), the most prevalent arrhythmia in clinical practice, presents a growing
global health concern, particularly with the aging population, as it is associated with …

Inflammatory signalling via the nod‐like receptor (NLR) family pyrin domain‐containing
protein‐3 (NLRP3) inflammasome has recently been implicated in the pathophysiology of …

Atrial fibrillation (AF) is a continually growing health-care burden that often presents together
with metabolic disorders, including diabetes mellitus and obesity. Current treatments often …

Atrial fibrillation (AF) is a cardiac disease characterized by disordered atrial electrical
activity. Atrial inflammation and fibrosis are involved in AF progression. Costunolide (COS) is …

Background Diabetes mellitus (DM) is a major risk factor for atrial structural remodeling and
atrial fibrillation (AF). Calpain activity is hypothesized to promote atrial remodeling and AF …