Host-microbiota interaction in intestinal stem cell homeostasis

H Wu, C Mu, L Xu, K Yu, L Shen, W Zhu - Gut Microbes, 2024 - Taylor & Francis
Intestinal stem cells (ISCs) play a pivotal role in gut physiology by governing intestinal
epithelium renewal through the precise regulation of proliferation and differentiation. The gut …

[HTML][HTML] Design strategies, advances and future perspectives of colon-targeted delivery systems for the treatment of inflammatory bowel disease

B Zheng, L Wang, Y Yi, J Yin, A Liang - Asian Journal of Pharmaceutical …, 2024 - Elsevier
Inflammatory bowel diseases (IBD) significantly contribute to high mortality globally and
negatively affects patients' qualifications of life. The gastrointestinal tract has unique …

[HTML][HTML] Colitis-induced small intestinal hypomotility is dependent on enteroendocrine cell loss in mice

Z Raouf, SN Steinway, D Scheese, CM Lopez… - Cellular and Molecular …, 2024 - Elsevier
Background & Aims The abdominal discomfort experienced by patients with colitis may be
attributable in part to the presence of small intestinal dysmotility, yet mechanisms linking …

Necrotizing Enterocolitis

J Weller, MES Sampah, AJG Salazar… - Principles of Neonatology, 2024 - Elsevier
Necrotizing enterocolitis (NEC) is an idiopathic, acute inflammatory bowel necrosis seen in
premature and critically ill infants. We have noted five clinical presentations of NEC (NEC …