Structural studies with crotoxin B from Crotalus durissus collilineatus venom suggest a heterodimeric assembly formed by two new isoforms
In accidents involving Crotalus snakes, the crotoxin complex (CTX) plays lethal action due to
its neurotoxic activity. On the other hand, CTX have potential biotechnological application …
its neurotoxic activity. On the other hand, CTX have potential biotechnological application …
Expanding anti-venom strategies: Camelid polyclonal antibodies with high capacity to recognize snake venom
BJC Farias, AM Kayano, MB Luiz, AMDE Lima… - Toxicon, 2024 - Elsevier
Camelid immunoglobulins represent a unique facet of antibody biology, challenging
conventional understandings of antibody diversification. IgG2 and IgG3 in particular are …
conventional understandings of antibody diversification. IgG2 and IgG3 in particular are …
Fraction of C. d. collilineatus venom containing crotapotin protects PC12 cells against MPP + toxicity by activating the NGF-signaling pathway
CP Bernardes, E Lopes Pinheiro, IG Ferreira… - Journal of Venomous …, 2024 - SciELO Brasil
Background: Parkinson's disease (PD) is the second most prevalent neurodegenerative
disease. There is no effective treatment for neurodegenerative diseases. Snake venoms are …
disease. There is no effective treatment for neurodegenerative diseases. Snake venoms are …