Practical Guidance for Clinical Microbiology Laboratories: Microbiologic diagnosis of implant-associated infections

MA Azad, R Patel - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
Implant-associated infections (IAIs) pose serious threats to patients and can be associated
with significant morbidity and mortality. These infections may be difficult to diagnose due, in …

Sonication protocols and their contributions to the microbiological diagnosis of implant-associated infections: a review of the current scenario

NDS Silva, BST De Melo, A Oliva… - Frontiers in Cellular and …, 2024 - frontiersin.org
Addressing the existing problem in the microbiological diagnosis of infections associated
with implants and the current debate about the real power of precision of sonicated fluid …

[HTML][HTML] How good are surgeons at disclosing periprosthetic joint infection at the time of revision, based on pre-and intra-operative assessment? A study on 16,922 …

O Lutro, MO Synnøve, MB Tjørhom, AM Fenstad… - Acta …, 2024 - ncbi.nlm.nih.gov
Background and purpose Revision due to infection, as reported to the Norwegian
Arthroplasty Register (NAR), is a surrogate endpoint to periprosthetic joint infection (PJI). We …

[HTML][HTML] Comparative transcriptomic analysis of Staphylococcus epidermidis associated with periprosthetic joint infection under in vivo and in vitro conditions

CR Fisher, TL Masters, S Johnson… - International Journal of …, 2024 - Elsevier
Staphylococcus epidermidis is part of the commensal microbiota of the skin and mucous
membranes, though it can also act as a pathogen in certain scenarios, causing a range of …

Differences in Diagnostic Sensitivity of Cultures Between Sample Types in Periprosthetic Joint Infections: A Systematic Review and Meta-Analysis

S Watanabe, E Kamono, H Choe, H Ike, Y Inaba… - The Journal of …, 2024 - Elsevier
Background Differences between the bacterial culture results of the preoperative fluid,
intraoperative tissue, and sonication fluid of implants in the diagnosis of periprosthetic joint …

Treatment of wound infections linked to neurosurgical implants

Y Wang, Y Wang, S Wang, S Hou, D Yu… - International Wound …, 2024 - Wiley Online Library
As neurosurgery has advanced technologically, more and more neurosurgical implants are
being employed on an aging patient population with several comorbidities. As a result, there …

Will previous antimicrobial therapy reduce the positivity rate of metagenomic next-generation sequencing in periprosthetic joint infections? A clinical study

L Hao, W Bian, Z Qing, T Ma, H Li, P Xu… - Frontiers in Cellular and …, 2024 - frontiersin.org
Background Metagenomic next-generation sequencing (mNGS) is a culture-independent
massively parallel DNA sequencing technology and it has been widely used for rapid …

The Antibacterial Properties of a Silver Multilayer Coating for the Prevention of Bacterial Biofilm Formation on Orthopedic Implants—An In Vitro Study

SWG van Hoogstraten, J Fechter, R Bargon… - Coatings, 2024 - mdpi.com
The prevention of biofilm formation on orthopedic implants is essential, as biofilms are the
main challenge in the effective treatment of periprosthetic joint infection (PJI). A silver …

Update on the role of pathology and laboratory medicine in diagnosing periprosthetic infection

FM Mazzella, Y Zhang, TW Bauer - Human Pathology, 2024 - Elsevier
Technological and implant design advances have helped reduce the frequency of aseptic
total joint arthroplasty failure, but periprosthetic joint infections (PJI) remain a clinical …

Modern Microbiological Methods to Detect Biofilm Formation in Orthopedy and Suggestions for Antibiotic Therapy, with Particular Emphasis on Prosthetic Joint …

P Mikziński, K Kraus, J Widelski, E Paluch - Microorganisms, 2024 - mdpi.com
Biofilm formation is a serious problem that relatively often causes complications in
orthopedic surgery. Biofilm-forming pathogens invade implanted foreign bodies and …