Wound‐triggered shape change microgels for the development of enhanced biomimetic function platelet‐like particles

E Chee, E Mihalko, K Nellenbach… - … Research Part A, 2024 - Wiley Online Library
Platelets play a pivotal role in hemostasis and wound healing and conditional shape change
is an important component of platelet functionality. In normal circumstances, platelets travel …

Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma

K Nellenbach, E Mihalko, S Nandi, DW Koch… - Science Translational …, 2024 - science.org
Uncontrolled bleeding after trauma represents a substantial clinical problem. The current
standard of care to treat bleeding after trauma is transfusion of blood products including …

[HTML][HTML] Heterogeneity of platelets and their responses

S Thomas, S Kelliher, A Krishnan - Research and Practice in Thrombosis …, 2024 - Elsevier
There has been increasing recognition of heterogeneity in blood platelets and their
responses, particularly in recent years, where next-generation technologies and advanced …