Background: Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in
patients with systemic sclerosis (SSc). To date, clinical practice guidelines regarding …

Interstitial lung diseases comprise a heterogenous range of diffuse lung disorders,
potentially resulting in pulmonary fibrosis. While idiopathic pulmonary fibrosis has been …

Pirfenidone and Nintedanib are specific drugs used against idiopathic pulmonary fibrosis
(IPF) that showed efficacy in non-IPF fibrosing interstitial lung diseases (ILD). Both drugs …

Ethnopharmacological relevance Bletilla striata, a traditional medicinal plant, has been
utilized as a folk medicine for many years because of its superior biological activity in China …

Systemic sclerosis (SSc) is a rare autoimmune disease characterized by a tripod combining
vasculopathy, fibrosis, and immune-mediated inflammatory processes. The prevalence of …

Background Interstitial lung disease (ILD) is one of the leading causes of mortality in patients
with systemic sclerosis (SSc). Serum biomarkers have been suggested as indicators for …

Connective tissue disease-associated interstitial lung disease (CTD-ILD) represents a group
of systemic autoimmune disorders characterized by immune-mediated organ dysfunction …

Skin thickening of early diffuse cutaneous systemic sclerosis (dcSSc) is in itself a major
source of pain, disability, and disfigurement. Skin involvement progresses and then tends to …

Doença pulmonar intersticial associada à doença do tecido conjuntivo (DPI-DTC)
representa um grupo de distúrbios autoimunes sistêmicos caracterizados por disfunção de …