Sepsis is a significant public health concern, particularly affecting individuals above 70
years in developed countries. This is a crucial fact due to the increasing aging population …

A dysregulated host response to infection causes organ dysfunction in sepsis and septic
shock, two potentially fatal diseases. They continue to be major worldwide health burdens …

OBJECTIVES: To identify research priorities in the management, epidemiology, outcome,
and pathophysiology of sepsis and septic shock. DESIGN: Shortly after publication of the …

The critical care management of patients after cardiac arrest is burdened by a lack of high-
quality clinical studies and the resultant lack of high-certainty evidence. This results in …

Purpose The efficacy of the 1-h bundle for emergency department (ED) patients with
suspected sepsis, which includes lactate measurement, blood culture, broad-spectrum …

Rationale: Sepsis management relies on fluid resuscitation avoiding fluid overload and its
related organ congestion. Objectives: To explore the influence of country income group on …

Sepsis is a time-dependent disease whose prognosis is influenced by early diagnosis and
therapeutic measures. Mortality from sepsis remains high, and for this reason, the guidelines …

The volume of oxygen drawn from systemic capillaries down a partial pressure gradient is
determined by the oxygen content of red blood cells (RBCs) and their oxygen-unloading …

Critical care medicine in the 21st century has witnessed remarkable advancements that
have significantly improved patient outcomes in intensive care units (ICUs). This abstract …

Over the past two decades, our understanding of the impact of acute kidney injury, disorders
of fluid balance, and their interplay have increased significantly. In recent years, the …