Ion channel P2X7 receptor in the progression of cancer
G Zhang, J Liao, Y Liu, F Zhu, H Huang… - Frontiers in …, 2024 - frontiersin.org
P2X7 receptor (P2X7) is a non-selective and ATP-sensitive ligand-gated cation channel.
Studies have confirmed that it is expressed in a variety of cells and correlates with their …
Studies have confirmed that it is expressed in a variety of cells and correlates with their …
Unexpected chronic lymphocytic leukemia B cell activation by bisphosphonates
Chronic lymphocytic leukemia (CLL) is a disease of the elderly, often presenting
comorbidities like osteoporosis and requiring, in a relevant proportion of cases, treatment …
comorbidities like osteoporosis and requiring, in a relevant proportion of cases, treatment …
Potential role of the P2X7 receptor in the proliferation of human diffused large B-cell lymphoma
X Yang, Y Ji, L Mei, W Jing, X Yang, Q Liu - Purinergic Signalling, 2024 - Springer
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of invasive non-
Hodgkin lymphoma. 60–70% of patients are curable with current chemoimmunotherapy …
Hodgkin lymphoma. 60–70% of patients are curable with current chemoimmunotherapy …
Oxidized ATP Suppresses B Lymphocyte Activity to Attenuate Antibody-mediated Rejection of Kidney Allografts in Mice
Y Yu, Z Bi, Q Jiang, S Huang, Y He, J Gai… - …, 2024 - journals.lww.com
Background. Antibody-mediated rejection (AMR) is a major cause of renal allograft
dysfunction and loss. Targeting B cells and/or donor-specific antibody removal using plasma …
dysfunction and loss. Targeting B cells and/or donor-specific antibody removal using plasma …
Purinergic P2X Receptors as Therapeutic Targets
Purinergic P2X receptors are ATP-gated ion channels involved in cation flux across
membranes. P2X receptors are assembled as trimers from three identical subunits …
membranes. P2X receptors are assembled as trimers from three identical subunits …