From treatable traits to GETomics in airway disease: moving towards clinical practice

A Papi, R Faner, I Pavord, F Baraldi… - European …, 2024 - Eur Respiratory Soc
The treatable traits approach represents a strategy for patient management. It is based on
the identification of characteristics susceptible to treatments or predictive of treatment …

Review of the Evidence for Pulmonary Rehabilitation in COPD: Clinical Benefits and Cost-Effectiveness

CE Lamberton, CL Mosher - Respiratory Care, 2024 - rc.rcjournal.com
COPD is a common and lethal chronic condition, recognized as a leading cause of death
worldwide. COPD is associated with significant morbidity and disability, particularly among …

Association of Acute Respiratory Disease Events with Quantitative Interstitial Abnormality Progression at CT in Individuals with a History of Smoking

B Choi, AA Díaz, R San José Estépar, N Enzer… - Radiology, 2024 - pubs.rsna.org
Background Acute respiratory disease (ARD) events are often thought to be airway-disease
related, but some may be related to quantitative interstitial abnormalities (QIAs), which are …

Cognitive and emotional responses to chronic obstructive pulmonary disease exacerbations and patterns of care seeking

ER Locke, RM Thomas, TL Simpson… - Annals of the …, 2024 - atsjournals.org
Rationale: Cognitive and emotional responses associated with care seeking for chronic
obstructive pulmonary disease (COPD) exacerbations are not well understood. Objectives …

[HTML][HTML] Exacerbation predictive modelling using real-world data from the myCOPD app

HMG Glyde, AM Blythin, TMA Wilkinson, IT Nabney… - Heliyon, 2024 - cell.com
Background Acute exacerbations of COPD (AECOPD) are episodes of breathlessness,
cough and sputum which are associated with the risk of hospitalisation, progressive lung …

[HTML][HTML] Musculoskeletal crosstalk in chronic obstructive pulmonary disease and comorbidities: Emerging roles and therapeutic potentials

K Mou, SMH Chan, R Vlahos - Pharmacology & Therapeutics, 2024 - Elsevier
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a multifaceted respiratory
disorder characterized by progressive airflow limitation and systemic implications. It has …

[HTML][HTML] Prevention of exacerbation in patients with moderate-to-very severe COPD with the intent to modulate respiratory microbiome: a pilot prospective, multi-center …

J Hua, Z Yang, Q Cheng, Y Han, Z Li, R Dai… - Frontiers in …, 2024 - frontiersin.org
Introduction Considering the role of bacteria in the onset of acute exacerbation of COPD
(AECOPD), we hypothesized that the use of influenza-Streptococcus pneumoniae …

RSV-related Community COPD Exacerbations and Novel Diagnostics: A Binational Prospective Cohort Study

DJ Wiseman, RS Thwaites, AI Ritchie… - American Journal of …, 2024 - atsjournals.org
Rationale: Respiratory syncytial virus (RSV) is a common global respiratory virus
increasingly recognized as a major pathogen in frail older adults and as a cause of chronic …

Risk factors for chronic obstructive pulmonary disease exacerbations among individuals without a history of recent exacerbations: a COPDGene analysis

MC Ferrera, CL Lopez, S Murray, RG Jain… - Annals of the …, 2024 - atsjournals.org
Rationale: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) are
detrimental events in the natural history of COPD, but the risk factors associated with future …

[HTML][HTML] Differences in cardiovascular risk and health-related quality of life in COPD patients according to clinical phenotype

AM Montiel, P Ruiz-Esteban, AD Del Río… - Scientific Reports, 2024 - nature.com
Chronic obstructive pulmonary disease (COPD) has a high prevalence and a major impact
on health-related quality of life (HRQL). COPD exacerbations are an important cause of …