Biological role of mitochondrial TLR4‐mediated NF‐κB signaling pathway in central nervous system injury

Z Wu, Y Song, Y Wang, H Zhou, L Chen… - Cell Biochemistry …, 2024 - Wiley Online Library
Previous studies suggested that central nervous system injury is often accompanied by the
activation of Toll‐like receptor 4/NF‐κB pathway, which leads to the upregulation of …

Blackberry extract prevents lipopolysaccharide-induced depressive-like behavior in female mice: implications for redox status, inflammation, and brain enzymes

SV Custódio, RC Piccoli, KCM Goularte… - Nutritional …, 2024 - Taylor & Francis
This study evaluated the effects of Rubus sp. extract on behavioral and neurochemical
parameters in female mice submitted to experimental model of depression induced by …

In Vitro Astroglial Dysfunction Induced by Neurotoxins: Mimicking Astrocytic Metabolic Alterations of Alzheimer's Disease

J Taday, FT Fróes, M Seady, CA Gonçalves, MC Leite - Metabolites, 2024 - mdpi.com
Astrocytes play fundamental roles in the maintenance of brain homeostasis. The dysfunction
of these cells is widely associated with brain disorders, which are often characterized by …

Diosmin inhibits neuroinflammation and improves cognitive deficit in lipopolysaccharide-mouse model of Alzheimer's disease

OA ADEOLUWA, FR ADENIYI, GO ADEOLUWA… - 2024 - researchsquare.com
Background: Neuroinflammation has been linked to some central alterations such as
cognitive and memory impairment which are prominent features of many neurodegenerative …