[HTML][HTML] TBK1 is paradoxical in tumor development: a focus on the pathway mediating IFN-I expression
B Wang, F Zhang, X Wu, M Ji - Frontiers in Immunology, 2024 - frontiersin.org
TANK-binding kinase 1 (TBK1) is a member of the IKK family and plays a crucial role in the
activation of non-canonical NF-κB signaling and type I interferon responses. The aberrant …
activation of non-canonical NF-κB signaling and type I interferon responses. The aberrant …
Crosstalk and Prospects of TBK1 in Inflammation
H Liu, Q Sheng, J Dan, X Xie - Immunological Investigations, 2024 - Taylor & Francis
Background TANK-binding kinase 1 (TBK1) is a pivotal mediator of innate immunity,
activated by receptors such as mitochondrial antiviral signaling protein (MAVS), stimulator of …
activated by receptors such as mitochondrial antiviral signaling protein (MAVS), stimulator of …
[HTML][HTML] The miR-7/EGFR axis controls the epithelial cell immunomodulation and regeneration and orchestrates the pathology in inflammatory bowel disease
J Zhao, M Guo, Y Yan, Y Wang, X Zhao, J Yang… - Journal of Advanced …, 2024 - Elsevier
Introduction The epithelial immunomodulation and regeneration are intrinsic critical events
against inflammatory bowel disease (IBD). MiR-7 is well documented as a promising …
against inflammatory bowel disease (IBD). MiR-7 is well documented as a promising …
[HTML][HTML] Viola yedoensis Makino alleviates lipopolysaccharide-induced intestinal oxidative stress and inflammatory response by regulating the gut microbiota and NF …
H Zhao, Y Huang, W Yang, C Huang, Z Ou, J He… - Ecotoxicology and …, 2024 - Elsevier
Abstract Viola yedoensis Makino (Vy) is a well-known traditional Chinese medicine widely
used to treat inflammatory diseases. However, the regulatory effects of dietary Vy …
used to treat inflammatory diseases. However, the regulatory effects of dietary Vy …
Qingchang Suppository Ameliorates Mucosal Inflammation in Ulcerative Colitis by Inhibiting the Differentiation and Effector Functions of Th1 and Th17 Cells
H Cao, H Liu, X Dai, B Shi, J Yuan, J Shan… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Qing Chang Suppository (QCS), a traditional
Chinese medicine formula, has been shown to effectively alleviate mucosal inflammation in …
Chinese medicine formula, has been shown to effectively alleviate mucosal inflammation in …
Amlexanox targeted inhibition of TBK1 regulates immune cell function to exacerbate DSS-induced inflammatory bowel disease
L Hui, M Huang, Q Dai1, C Miao, Y Yang… - Clinical and …, 2024 - academic.oup.com
Amlexanox (ALX) is a small molecule drug for the treatment of inflammatory, autoimmune,
metabolic and tumor diseases. At present, there are no studies on whether ALX has a …
metabolic and tumor diseases. At present, there are no studies on whether ALX has a …
[HTML][HTML] RRP8, associated with immune infiltration, is a prospective therapeutic target in hepatocellular carcinoma
K You, X Du, Y Zhao, F Wen, Z Lu, H Fan - Journal of Cancer Research …, 2024 - Springer
Background Ribosomal RNA Processing 8 (RRP8) is a nucleolar Rossman fold-like
methyltransferase that exhibits increased expression in many malignant tumours. However …
methyltransferase that exhibits increased expression in many malignant tumours. However …
TRIM27 Promotes Endothelial Progenitor Cell Apoptosis in Patients with In-Stent Restenosis by Ubiquitinating TBK1
B Liu, H Wang, W Xie, T Gong - Applied Biochemistry and Biotechnology, 2024 - Springer
Abstract Approximately 2–10% in-stent restenosis (ISR) may occur following percutaneous
coronary intervention (PCI) despite the use of modern drug-eluting stents (DES); thus, our …
coronary intervention (PCI) despite the use of modern drug-eluting stents (DES); thus, our …
Potential prognostic value of ITPR1 in thyroid carcinoma: An integrated analysis
T Qiao, X Yu, Y Han, C Jia, Y Yin, X Cong, Z Lv - Gene Reports, 2024 - Elsevier
Abstract Purpose Inositol 1, 4, 5-trisphosphate receptor type1 (ITPR1) is reported to play an
important role in malignancy. We aim to explore the potential role of ITPR1 in thyroid …
important role in malignancy. We aim to explore the potential role of ITPR1 in thyroid …