Enzymatic control of intermolecular interactions for generating synthetic nanoarchitectures in cellular environment
Nanoarchitectonics, as a technology to arrange nano-sized structural units such as
molecules in a desired configuration, requires nano-organization, which usually relies on …
molecules in a desired configuration, requires nano-organization, which usually relies on …
[HTML][HTML] Atomic structures of naphthalene dipeptide micelles unravel mechanisms of assembly and gelation
Peptide-based biopolymers have gained increasing attention due to their versatile
applications. A naphthalene dipeptide (2NapFF) can form chirality-dependent tubular …
applications. A naphthalene dipeptide (2NapFF) can form chirality-dependent tubular …
[HTML][HTML] Two distinct archaeal type IV pili structures formed by proteins with identical sequence
J Liu, GN Eastep, V Cvirkaite-Krupovic… - Nature …, 2024 - nature.com
Abstract Type IV pili (T4P) represent one of the most common varieties of surface
appendages in archaea. These filaments, assembled from small pilin proteins, can be many …
appendages in archaea. These filaments, assembled from small pilin proteins, can be many …
[HTML][HTML] From structural polymorphism to structural metamorphosis of the coat protein of flexuous filamentous potato virus Y
L Kavčič, A Kežar, N Koritnik, MT Žnidarič… - Communications …, 2024 - nature.com
The structural diversity and tunability of the capsid proteins (CPs) of various icosahedral and
rod-shaped viruses have been well studied and exploited in the development of smart …
rod-shaped viruses have been well studied and exploited in the development of smart …
[HTML][HTML] Directly visualizing individual polyorganophosphazenes and their single-chain complexes with proteins
R Hlushko, E Pozharski, VM Prabhu… - Communications …, 2024 - nature.com
Polyorganophosphazenes are water-soluble macromolecules with immunoadjuvant activity
that self-assemble with proteins to enable biological functionality. Direct imaging by …
that self-assemble with proteins to enable biological functionality. Direct imaging by …
Assessment of the Enzymatic Dephosphorylation Kinetics in the Assemblies of a Phosphopentapeptide that Forms Intranuclear Nanoribbons
Although the formation of peptide assemblies catalyzed by alkaline phosphatase (ALP) has
received increasing attention in inhibiting cancer cells, the detailed enzyme kinetics of the …
received increasing attention in inhibiting cancer cells, the detailed enzyme kinetics of the …
Synthesis of Helical-Shaped Axially Chiral Bisoxime Ethers via Chiral Phosphoric-Acid-Catalyzed Sequential Enantioselective Condensations
B Shao, B Ren, W Jiang, L Shi - Organic Letters, 2024 - ACS Publications
A successful synthesis of helical-shaped axially chiral bisoxime ethers is reported. This
approach utilized symmetric L-shaped diketone scaffolds as carbonyl components for the …
approach utilized symmetric L-shaped diketone scaffolds as carbonyl components for the …
Nano-Assembled Polyphosphazene Delivery System Enables Effective Intranasal Immunization with Nipah Virus Subunit Vaccine
The ultimate vaccine against infections caused by Nipah virus should be capable of
providing protection at the respiratory tract─ the most probable port of entry for this …
providing protection at the respiratory tract─ the most probable port of entry for this …
Assembly of peptide nanostructures with controllable sizes
D Cheng, F Jia, YB Jiang, VP Conticello, T Jiang - Nano Research, 2024 - Springer
Controlled peptide assembly offers significant promise to develop synthetic supramolecular
nanostructures to display material and biological properties that mimic protein assemblies in …
nanostructures to display material and biological properties that mimic protein assemblies in …
Near-atomic-resolution structure of J-aggregated helical light-harvesting nanotubes
Cryo-electron microscopy has delivered a resolution revolution for biological self-
assemblies, yet only a handful of structures have been solved for synthetic supramolecular …
assemblies, yet only a handful of structures have been solved for synthetic supramolecular …