Enzymatic control of intermolecular interactions for generating synthetic nanoarchitectures in cellular environment

W Tan, Q Zhang, M Lee, W Lau, B Xu - Science and Technology of …, 2024 - Taylor & Francis
Nanoarchitectonics, as a technology to arrange nano-sized structural units such as
molecules in a desired configuration, requires nano-organization, which usually relies on …

[HTML][HTML] Atomic structures of naphthalene dipeptide micelles unravel mechanisms of assembly and gelation

RR Sonani, S Bianco, B Dietrich, J Doutch… - Cell Reports Physical …, 2024 - cell.com
Peptide-based biopolymers have gained increasing attention due to their versatile
applications. A naphthalene dipeptide (2NapFF) can form chirality-dependent tubular …

[HTML][HTML] Two distinct archaeal type IV pili structures formed by proteins with identical sequence

J Liu, GN Eastep, V Cvirkaite-Krupovic… - Nature …, 2024 - nature.com
Abstract Type IV pili (T4P) represent one of the most common varieties of surface
appendages in archaea. These filaments, assembled from small pilin proteins, can be many …

[HTML][HTML] From structural polymorphism to structural metamorphosis of the coat protein of flexuous filamentous potato virus Y

L Kavčič, A Kežar, N Koritnik, MT Žnidarič… - Communications …, 2024 - nature.com
The structural diversity and tunability of the capsid proteins (CPs) of various icosahedral and
rod-shaped viruses have been well studied and exploited in the development of smart …

[HTML][HTML] Directly visualizing individual polyorganophosphazenes and their single-chain complexes with proteins

R Hlushko, E Pozharski, VM Prabhu… - Communications …, 2024 - nature.com
Polyorganophosphazenes are water-soluble macromolecules with immunoadjuvant activity
that self-assemble with proteins to enable biological functionality. Direct imaging by …

Assessment of the Enzymatic Dephosphorylation Kinetics in the Assemblies of a Phosphopentapeptide that Forms Intranuclear Nanoribbons

Y Qiao, G Wu, Z Liu, H He, W Tan, B Xu - Biomacromolecules, 2024 - ACS Publications
Although the formation of peptide assemblies catalyzed by alkaline phosphatase (ALP) has
received increasing attention in inhibiting cancer cells, the detailed enzyme kinetics of the …

Synthesis of Helical-Shaped Axially Chiral Bisoxime Ethers via Chiral Phosphoric-Acid-Catalyzed Sequential Enantioselective Condensations

B Shao, B Ren, W Jiang, L Shi - Organic Letters, 2024 - ACS Publications
A successful synthesis of helical-shaped axially chiral bisoxime ethers is reported. This
approach utilized symmetric L-shaped diketone scaffolds as carbonyl components for the …

Nano-Assembled Polyphosphazene Delivery System Enables Effective Intranasal Immunization with Nipah Virus Subunit Vaccine

VH Leyva-Grado, A Marin, R Hlushko… - ACS Applied Bio …, 2024 - ACS Publications
The ultimate vaccine against infections caused by Nipah virus should be capable of
providing protection at the respiratory tract─ the most probable port of entry for this …

Assembly of peptide nanostructures with controllable sizes

D Cheng, F Jia, YB Jiang, VP Conticello, T Jiang - Nano Research, 2024 - Springer
Controlled peptide assembly offers significant promise to develop synthetic supramolecular
nanostructures to display material and biological properties that mimic protein assemblies in …

Near-atomic-resolution structure of J-aggregated helical light-harvesting nanotubes

AP Deshmukh, W Zheng, C Chuang, AD Bailey… - Nature Chemistry, 2024 - nature.com
Cryo-electron microscopy has delivered a resolution revolution for biological self-
assemblies, yet only a handful of structures have been solved for synthetic supramolecular …