Combating Parkinson's disease with plant-derived polyphenols: Targeting oxidative stress and neuroinflammation

RM Gahtani, S Shoaib, U Hani, R Jayachithra… - Neurochemistry …, 2024 - Elsevier
Parkinson's disease (PD) is a devastating neurodegenerative disorder predominantly
affecting the elderly, characterized by the loss of dopaminergic neurons in the substantia …

A Comprehensive Review of Essential Oils and Their Pharmacological Activities in Neurological Disorders: Exploring Neuroprotective Potential

M Qneibi, S Bdir, C Maayeh, M Bdair… - Neurochemical …, 2024 - Springer
Numerous studies have demonstrated essential oils' diverse chemical compositions and
pharmacological properties encompassing antinociceptive, anxiolytic-like, and …

Tangeretin Attenuates Cerebral Ischemia–Reperfusion-Induced Neuronal Pyroptosis by Inhibiting AIM2 Inflammasome Activation via Regulating NRF2

G You, L Zheng, Y Zhang, Y Zhang, Y Wang, W Guo… - Inflammation, 2024 - Springer
Pyroptosis is closely involved in the pathopoiesis of cerebral ischemia and reperfusion (I/R)
injury which seriously dangers human's life. Studies report that tangeretin (TANG), which is …

A protein–miRNA biomic analysis approach to explore neuroprotective potential of nobiletin in human neural progenitor cells (hNPCs)

S Jahan, UA Ansari, AK Srivastava… - Frontiers in …, 2024 - frontiersin.org
Chemical-induced neurotoxicity is increasingly recognized to accelerate the development of
neurodegenerative disorders (NDs), which pose an increasing health burden to society …

Vacuolar proteomic analysis reveals tonoplast transporters for accumulation of citric acid and sugar in citrus fruit

Z Mao, Y Wang, M Li, S Zhang, Z Zhao, Q Xu… - Horticulture …, 2024 - academic.oup.com
Vacuole largely dictates the fruit taste and flavor, as most of the sugars and organic acids
are stored in the vacuoles of the fruit. However, difficulties associated with vacuole …

Insights on the extraction and analysis of phenolic compounds from citrus fruits: green perspectives and current status

VL Sanches, LM de Souza Mesquita… - Critical Reviews in …, 2024 - Taylor & Francis
Citrus fruits (CF) are highly consumed worldwide, fresh, processed, or prepared as juices
and pies. To illustrate the high economic importance of CF, the global production of these …

Green and efficient approach to extract bioactive flavonoids with antioxidant, antibacterial, antiglycation, and enzyme inhibitory activities from navel orange peel

C Lai, M Huang, Q Xiong, Y Liang, Y Jiang… - … Chemistry and Pharmacy, 2024 - Elsevier
Numerous previous studies have reported the extraction of flavonoids from orange peels,
but a green and efficient approach suitable for the large-scale industrial production of …

Ameliorating effect of Citrus trifoliata L. fruits extract on motor incoordination, neurodegeneration and oxidative stress in Parkinson's disease model

MA Abdel-Kawy, BE Aboulhoda, CG Michel… - Nutritional …, 2024 - Taylor & Francis
Background Citrus trifoliate fruit (also known as Trifoliate orange) is one of the commercially-
cultivated Citrus genus of plants belonging to the Rutaceae family. It has been traditionally …

Phytochemistry, pharmacological properties and pharmacokinetics of Citri Reticulatae Pericarpium: A systematic review

X Zhang, Y Jiang, J Zeng, X Li, H Xie, R Yang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Citri Reticulatae Pericarpium (CRP), known as
Chen Pi in China, is the most commonly used medicine for regulating qi. As a traditional …

Revealing Comprehensive Food Functionalities and Mechanisms of Action through Machine Learning

N Inoue, T Shibata, Y Tanaka, H Taguchi… - Journal of Chemical …, 2024 - ACS Publications
Foods possess a range of unexplored functionalities; however, fully identifying these
functions through empirical means presents significant challenges. In this study, we have …