Bispecific antibodies (bsAbs) enable novel mechanisms of action and/or therapeutic
applications that cannot be achieved using conventional IgG-based antibodies …

In vitro and in vivo models play integral roles in preclinical drug research, evaluation, and
precision medicine. In vitro models primarily involve research platforms based on cultured …

A comprehensive investigation of ovarian cancer (OC) progression at the single-cell level is
crucial for enhancing our understanding of the disease, as well as for the development of …

Lysine acetyltransferases (KATs) are a family of epigenetic enzymes involved in the
regulation of gene expression; they represent a promising class of emerging drug targets …

Purpose: To overcome the limited efficacy of immune checkpoint blockade, there is a need
to find novel cancer immunotherapeutic strategies for the optimal treatment of cancer. The …

The relationship between CD276 and malignancies of the female reproductive system has
previously been controversial. The purpose of this study was to evaluate the predictive value …

Background Recent studies have demonstrated that APOC1 is associated with cancer
progression, exerting cancer-promoting and immune infiltration-promoting effects …

Introduction Immunotherapies have revolutionized cancer treatment, but often fail to produce
desirable therapeutic outcomes in all patients. Due to the inter-patient heterogeneity and …

Immune system imbalances contribute to the pathogenesis of several different diseases, and
immunotherapy shows great therapeutic efficacy against tumours and infectious diseases …

The occurrence of ovarian cancer (OC) is a major factor in women's mortality rates. Despite
progress in medical treatments, like new drugs targeting homologous recombination …