KIRREL promotes the proliferation of gastric cancer cells and angiogenesis through the PI3K/AKT/mTOR pathway

T Wang, S Chen, Z Wang, S Li, X Fei… - Journal of Cellular …, 2024 - Wiley Online Library
Anti‐angiogenesis is a promising therapeutic strategy for delaying tumour progression that
offers, new hope for gastric cancer targeted therapy. The purpose of this study was to …

Neph1 is required for neurite branching and is negatively regulated by the PRRXL1 homeodomain factor in the developing spinal cord dorsal horn

J Baltar, RM Miranda, M Cabral, S Rebelo… - Neural …, 2024 - Springer
The cell-adhesion molecule NEPH1 is required for maintaining the structural integrity and
function of the glomerulus in the kidneys. In the nervous system of Drosophila and C …

Phospholipid scramblase 1: an essential component of the nephrocyte slit diaphragm

V Castillo-Mancho, A Atienza-Manuel… - Cellular and Molecular …, 2024 - Springer
Blood ultrafiltration in nephrons critically depends on specialized intercellular junctions
between podocytes, named slit diaphragms (SDs). Here, by studying a homologous …

The Immunosuppressive Drug LF15-0195 Acts Also on Glomerular Lesions, by a Change in Cytoskeleton Distribution in Podocyte

L Le Berre, G Tilly, P Pilet, S Brouard… - American Journal of …, 2024 - karger.com
Abstract Introduction: Buffalo/Mna rats spontaneously develop nephrotic syndrome (NS)
which recurs after renal transplantation. The immunosuppressive drug LF15-0195 can …

A molecular mechanism for angiotensin II receptor blocker‐mediated slit membrane protection: Angiotensin II increases nephrin endocytosis via AT1‐receptor …

E Königshausen, UM Zierhut, M Ruetze… - The FASEB …, 2024 - Wiley Online Library
Albuminuria is characterized by a disruption of the glomerular filtration barrier, which is
composed of the fenestrated endothelium, the glomerular basement membrane, and the slit …

Gene deletions in complement factor H related protein gene locus and kidney transplantation

S Markkinen, I Lokki, I Helantera, J Ritari, J Partanen… - medRxiv, 2024 - medrxiv.org
We recently reported that a homozygous deletion in the complement factor H related (CFHR)
protein gene locus predisposed kidney transplant patients to allograft rejection. As donors …

[PDF][PDF] EXTENDED HISTOCOMPATIBILITY: GENOMIC PREDICTION OF KIDNEY TRANSPLANT OUTCOMES

S Markkinen - 2024 - helda.helsinki.fi
EXTENDED HISTOCOMPATIBILITY: GENOMIC PREDICTION OF KIDNEY TRANSPLANT
OUTCOMES Page 1 Finnish Red Cross Blood Service and The Doctoral School in Health Sciences …