Oxygen Targets in Neonatal Pulmonary Hypertension: Individualized,“Precision-Medicine” Approach

S Lakshminrusimha, SH Abman - Clinics in …, 2024 - perinatology.theclinics.com
Oxygen is a specific and potent pulmonary vasodilator. At the microvascular level, hypoxic
pulmonary vasoconstriction (HPV) is physiologically protective mechanism that limits blood …

The role of point-of-care ultrasound in the management of neonates with congenital diaphragmatic hernia

C Maddaloni, DU De Rose, S Ronci, F Pugnaloni… - Pediatric …, 2024 - nature.com
In the last few years, current evidence has supported the use of point-of-care ultrasound
(POCUS) for a number of diagnostic and procedural applications. Considering the valuable …

Long-term outcome of children with newly diagnosed pulmonary arterial hypertension: results from the global TOPP registry

MJ Ploegstra, DD Ivy, M Beghetti… - … Journal-Quality of …, 2024 - academic.oup.com
Abstract Background and aims The Tracking Outcomes and Practice in Pediatric Pulmonary
Hypertension (TOPP) registry is a global network established to gain insights into the …

Inhaled nitric oxide in neonatal pulmonary hypertension

MW Cookson, JP Kinsella - Clinics in Perinatology, 2024 - perinatology.theclinics.com
Three decades since the first pilot studies showed improvement in oxygenation with the use
of inhaled nitric oxide (iNO) in term neonates with persistent pulmonary hypertension of the …

Treating very preterm European infants with inhaled nitric oxide increased in‐hospital mortality but did not affect neurodevelopment at 5 years of age

V Siljehav, A Gudmundsdottir, J Tjerkaski… - Acta …, 2024 - Wiley Online Library
Aim We examined the outcomes of using inhaled nitric oxide (iNO) to treat very preterm born
(VPT) infants across Europe. Methods This was a sub‐study of the Screening to Improve …

Correlating Severity of Pulmonary Hypertension by Echocardiogram with Mortality in Premature Infants with Bronchopulmonary Dysplasia

RD Torok, RA Gardner, PCA Barker… - American Journal of …, 2024 - thieme-connect.com
Objective Bronchopulmonary dysplasia (BPD) is the most common complication of preterm
birth. Infants with BPD are at increased risk for pulmonary hypertension (PH). Cardiac …

Assessing the role of tracheostomy placement in bronchopulmonary dysplasia with pulmonary hypertension

TD Hicks, J Cameron, S Wang, A Ashrafi… - Journal of …, 2024 - nature.com
Objective Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth
and is associated with abnormal vasculature that contributes to pulmonary hypertension …

Early cardiac function and death, severe bronchopulmonary dysplasia and pulmonary hypertension in extremely preterm infants

SS Moore, G De Carvalho Nunes, A Dancea… - Pediatric …, 2024 - nature.com
Background Association between early cardiac function and neonatal outcomes are
scarcely reported. The aim of the current study was to describe this association with death …

First-year outcomes of very low birth weight preterm singleton infants with hypoxemic respiratory failure treated with milrinone and inhaled nitric oxide (iNO) compared …

YT Chang, JR Liu, WM Chen, CN Tseng, LC See - Plos one, 2024 - journals.plos.org
Background Inhaled nitric oxide (iNO) has a beneficial effect on hypoxemic respiratory
failure. The increased use of concurrent iNO and milrinone was observed. We aimed to …

Long-term outcomes of infants with severe BPD

JM Collaco, SA McGrath-Morrow - Seminars in Perinatology, 2024 - Elsevier
Preterm birth disrupts the normal sequence of lung development. Additionally, interventions
that support gas exchange, including positive pressure ventilation and supplemental oxygen …