Induction of mitochondrial toxicity by non-steroidal anti-inflammatory drugs (NSAIDs): The ultimate trade-off governing the therapeutic merits and demerits of these …

S Mazumder, S Bindu, S Debsharma… - Biochemical …, 2024 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are most extensively used over-the-counter
FDA-approved analgesic medicines for treating inflammation, musculoskeletal pain, arthritis …

Pseudomonas aeruginosa in chronic lung disease: untangling the dysregulated host immune response

R Nickerson, CS Thornton, B Johnston… - Frontiers in …, 2024 - frontiersin.org
Pseudomonas aeruginosa is a highly adaptable opportunistic pathogen capable of
exploiting barriers and immune defects to cause chronic lung infections in conditions such …

A randomised trial of oral prednisone for cystic fibrosis pulmonary exacerbation treatment

V Waters, M Shaw, L Perrem, BS Quon… - European …, 2024 - Eur Respiratory Soc
Background Elevated markers of systemic and pulmonary inflammation are associated with
failure to recover lung function following pulmonary exacerbations in people with cystic …

Epithelial responses to CFTR modulators are improved by inflammatory cytokines and impaired by anti-inflammatory drugs

T Rehman, AA Pezzulo, AL Thurman, RL Zemans… - JCI …, 2024 - Am Soc Clin Investig
Cystic fibrosis (CF) is a genetic disorder that disrupts CF transmembrane conductance
regulator (CFTR) anion channels and impairs airway host defenses. Airway inflammation is …

IBPA a mutual prodrug of ibuprofen and acetaminophen alleviates inflammation, immune dysregulation and fibrosis in preclinical models of systemic sclerosis

AR de Almeida, FJBM Junior, AT Dantas… - International …, 2024 - Elsevier
Systemic sclerosis (SSc) is a devastating autoimmune illness with a wide range of clinical
symptoms, including vascular abnormalities, inflammation, and persistent and progressive …

S3-Leitlinie: Lungenerkrankung bei Mukoviszidose–Pseudomonas aeruginosa

C Schwarz, J Bend, H Hebestreit, M Hogardt… - …, 2024 - thieme-connect.com
Mukoviszidose (Cystic Fibrosis, CF) ist die häufigste autosomal-rezessiv vererbte
Multisystemerkrankung. In Deutschland sind mind. 8000 Menschen betroffen. Die …

Promising Role of Theranostic Nanoparticles in Lung Diseases

MS Angeline, V Ernest, N John - Nanoparticles in Healthcare …, 2024 - books.google.com
The role of nanoparticles is inevitable in the medical sector in the present era of technology.
Though the field of medicine deals with the diagnosis and treatment of various diseases with …

[HTML][HTML] Pharmacologic Management of Cystic Fibrosis

S Brown - US Pharm, 2024 - uspharmacist.com
Cystic fibrosis (CF) is a common genetic disorder caused by mutations in the cystic fibrosis
transmembrane conductance regulator (CFTR) gene, resulting in altered function of anion …

Method of reducing pulmonary exacerbations in respiratory disease patients

S Ahuja, R Grosswald, GS Duncan… - US Patent …, 2024 - Google Patents
GERJIEKMNDGSCS-DQEYMECFSA-N 4-[[(1s, 4s)-2-[[4-[4-(1, 3-oxazol-2-yl) phenoxy]
phenyl] methyl]-2, 5-diazabicyclo [2.2. 1] heptan-5-yl] methyl] benzoic acid Chemical …

[引用][C] S3-Leitlinie: Lungenerkrankung bei Mukoviszidose–

UM der Havel