Adult outcomes of urinary, sexual functions and fertility after pediatric management of differences in sex development: Who should be followed and how?

N Kalfa, J Nordenström, G De Win… - Journal of Pediatric …, 2024 - Elsevier
The management of Differences of Sex Development (DSD) has evolved considerably in
recent years. The questioning of systematic early childhood treatment of DSD requires a …

[HTML][HTML] Maternal exposure to dibutyl phthalate (DBP) impairs angiogenesis and AR signalling pathway through suppression of TGFB1I1 in hypospadias offspring

L Wu, F Shi, Y Zhang, X Xu, Z Xie, S Hua, S Xia… - Ecotoxicology and …, 2024 - Elsevier
Early exposure to dibutyl phthalate (DBP) can cause hypospadias in newborn foetuses.
However, the underlying molecular mechanism is not well defined. Aberrant angiogenesis is …

Effects of sex hormones on vascular reactivity in boys with hypospadias

AK Lucas-Herald, AC Montezano… - The Journal of …, 2024 - academic.oup.com
Background Arteries from boys with hypospadias demonstrate hypercontractility and
impaired vasorelaxation. The role of sex hormones in these responses in unclear. Aims We …

Intracavernosal pressure of the erect penis in children with hypospadias

D Ben-Meir, F Abu Sbaih, M Frumer - International journal of impotence …, 2024 - nature.com
This study objective is to examine the intracavernosal pressure (ICP) in hypospadias boys
with and without previous corporotomies. Retrospectively, the ICPs that were measured …

Retrospective studies and quantitative proteomics reveal that abnormal expression of blood pressure, blood lipids, and coagulation related proteins is associated with …

K Zhang, S Wang, Y Qiu, B Bai, Q Zhang, X Xie - Human Genetics, 2024 - Springer
Hypospadias refers to the abnormal position of the male urethral orifice, which not only
leads to urination disorder but also causes sexual dysfunction in adulthood. However, the …