Sex differences in renal transporters: assessment and functional consequences

AA McDonough, AN Harris, L Xiong… - nature reviews …, 2024 - nature.com
Mammalian kidneys are specialized to maintain fluid and electrolyte homeostasis. The
epithelial transport processes along the renal tubule that match output to input have long …

Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease

G Fredman, CN Serhan - Nature Reviews Cardiology, 2024 - nature.com
Timely resolution of the acute inflammatory response (or inflammation resolution) is an
active, highly coordinated process that is essential to optimal health. Inflammation resolution …

An enhanced ResNet-50 deep learning model for arrhythmia detection using electrocardiogram biomedical indicators

R Anand, SV Lakshmi, D Pandey, BK Pandey - Evolving Systems, 2024 - Springer
Electrocardiogram (ECG) is one among the most common detecting techniques in the
analysis and detection of cardiac arrhythmia adopted due to its cost efficiency and simplicity …

Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence

SA Mahoney, R Venkatasubramanian, MA Darrah… - Aging …, 2024 - Wiley Online Library
Cellular senescence and the senescence‐associated secretory phenotype (SASP)
contribute to age‐related arterial dysfunction, in part, by promoting oxidative stress and …

Device-measured physical activity and cardiometabolic health: the Prospective Physical Activity, Sitting, and Sleep (ProPASS) consortium

JM Blodgett, MN Ahmadi, AJ Atkin… - European Heart …, 2024 - academic.oup.com
Abstract Background and Aims Physical inactivity, sedentary behaviour (SB), and
inadequate sleep are key behavioural risk factors of cardiometabolic diseases. Each …

Recent advances in polygenic scores: translation, equitability, methods and FAIR tools

R Xiang, M Kelemen, Y Xu, LW Harris, H Parkinson… - Genome Medicine, 2024 - Springer
Polygenic scores (PGS) can be used for risk stratification by quantifying individuals' genetic
predisposition to disease, and many potentially clinically useful applications have been …

New cardiovascular disease prediction approach using support vector machine and quantum-behaved particle swarm optimization

EI Elsedimy, SMM AboHashish, F Algarni - Multimedia Tools and …, 2024 - Springer
Cardiovascular disease (CVD) is one of the leading causes of death worldwide. Early
detection of CVD reduces the risk of a heart attack and increases the chance of recovery …

Ginkgolide B attenuates cerebral ischemia-reperfusion injury via inhibition of ferroptosis through disrupting NCOA4-FTH1 interaction

Y Yang, Q Wu, X Shan, H Zhou, J Wang, Y Hu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cerebral ischemia/reperfusion (I/R) injury is a major cause
of neuronal damage and death. Ginkgolide B (GB) has been shown to exhibit …

Role of the intestinal microbiome and its therapeutic intervention in cardiovascular disorder

A Luqman, A Hassan, M Ullah, S Naseem… - Frontiers in …, 2024 - frontiersin.org
The gut microbiome is a heterogeneous population of microbes comprising viruses,
bacteria, fungi, and protozoa. Such a microbiome is essential for sustaining host equilibrium …

[HTML][HTML] The role and therapeutic potential of nuclear factor κB (NF-κB) in ischemic stroke

G Xu, F Dong, L Su, ZX Tan, M Lei, L Li, D Wen… - Biomedicine & …, 2024 - Elsevier
Stroke is a prevalent cerebrovascular condition with a global impact, causing significant
rates of illness and death. Despite extensive research, the available treatment options for …