Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexities
S Ahuja, S Zaheer - Cell Biology International, 2024 - Wiley Online Library
Physiological embryogenesis and adult tissue homeostasis are regulated by transforming
growth factor‐β (TGF‐β), an evolutionarily conserved family of secreted polypeptide factors …
growth factor‐β (TGF‐β), an evolutionarily conserved family of secreted polypeptide factors …
[HTML][HTML] Wnt/β-catenin signaling pathway in carcinogenesis and cancer therapy
P Song, Z Gao, Y Bao, L Chen, Y Huang, Y Liu… - Journal of Hematology & …, 2024 - Springer
The Wnt/β-catenin signaling pathway plays a crucial role in various physiological processes,
encompassing development, tissue homeostasis, and cell proliferation. Under normal …
encompassing development, tissue homeostasis, and cell proliferation. Under normal …
[HTML][HTML] Selective microRNA expression of exosomes from retinal pigment epithelial cells by oxidative stress
Z Zhang, Q Gu, L Chen, D Yuan, X Gu, H Qian, P Xie… - Vision Research, 2024 - Elsevier
The function of exosomal miRNAs (miRs) in retinal degeneration is largely unclear. We were
aimed to investigate the functions of exosomes as well as their miRs derived from retinal …
aimed to investigate the functions of exosomes as well as their miRs derived from retinal …
Targeting SMAD3 Improves Response to Oxaliplatin in Esophageal Adenocarcinoma Models by Impeding DNA Repair
Purpose: TGFβ signaling is implicated in the progression of most cancers, including
esophageal adenocarcinoma (EAC). Emerging evidence indicates that TGFβ signaling is a …
esophageal adenocarcinoma (EAC). Emerging evidence indicates that TGFβ signaling is a …
[HTML][HTML] MicroRNA as a potential diagnostic and prognostic biomarker in brain gliomas: a systematic review and meta-analysis
Introduction Brain neoplasms and central nervous system (CNS) disorders, particularly
gliomas, have shown a notable increase in incidence over the last three decades, posing …
gliomas, have shown a notable increase in incidence over the last three decades, posing …
[HTML][HTML] Death-associated protein 3 in cancer—discrepant roles of DAP3 in tumours and molecular mechanisms
H Song, H Liu, X Wang, Y Yang, X Zhao… - Frontiers in …, 2024 - frontiersin.org
Cancer, ranks as the secondary cause of death, is a group of diseases that are
characterized by uncontrolled tumor growth and distant metastasis, leading to increased …
characterized by uncontrolled tumor growth and distant metastasis, leading to increased …
SPG21, a potential oncogene targeted by miR-128-3p, amplifies HBx-induced carcinogenesis and chemoresistance via activation of TRPM7-mediated JNK pathway …
P Zhou, W Yao, L Liu, Q Yan, X Chen, X Wei, S Ding… - Cellular Oncology, 2024 - Springer
Purpose Chronic hepatitis B virus (HBV) infection is the primary risk factor for the malignant
progression of hepatocellular carcinoma (HCC). It has been reported that HBV X protein …
progression of hepatocellular carcinoma (HCC). It has been reported that HBV X protein …