In vitro 3D models are advanced biological tools that have been established to overcome
the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D …

Recombinant collagen is a pivotal topic in foundational biological research and epitomizes
the application of critical bioengineering technologies. These technological advancements …

Genome-wide CRISPR screens have provided a systematic way to identify essential genetic
regulators of a phenotype of interest with single-cell resolution. However, most screens use …

While existing synthetic technologies for ex vivo T-cell activation face challenges like
suboptimal expansion rates and low effectiveness, artificial antigen-presenting cells …

Progress in the discovery of potent antibodies for therapeutic and research purposes has
been accelerated by mining the antibody repertoire of plasma cells and plasmablasts …

Cancer has become one of the most important factors threatening human health, and the
global cancer burden has been increasing rapidly. Immunotherapy has become another …

The microfluidic chip-based nucleic acid detection method significantly improves the
sensitivity since it precisely controls the microfluidic flow in microchannels. Nonetheless …

Adoptive cellular immunotherapy using immune cells expressing chimeric antigen receptors
(CARs) is a highly specific anti-tumor immunotherapy that has shown promise in the …

It is challenging to prepare sample pretreatment materials with simple use, strong selectivity
and satisfactory enrichment performance. In this study, the antibody (3D4) that can …

Abstract Analysis of single cancer cells is critical to obtain accurate patient diagnosis and
prognosis. In this work, we report the selective dielectrophoretic capture and electrochemical …