Monogenic kidney diseases result from an abundance of potential genes carrying
pathogenic variants. These conditions are primarily recognized for manifesting as kidney …

Fabry disease (FD) is a multiorgan lysosomal storage disorder caused by mutations in the
alfa-galactosidase A (GLA) gene. Pathogenic GLA mutations lead to impaired or even lost …

Anderson–Fabry disease is a lysosomal storage disorder caused by mutations in the GLA
gene, which encodes the enzyme α-galactosidase A. The GLA gene is located on the X …

Simple Summary Although mRNA injection-based protein supplementation has emerged as
a feasible strategy for treating Fabry disease, whether the administration of lipid nanoparticle …

The process of SARS-CoV-2 infection, responsible for the COVID-19 pandemic, is carried
out through different steps, with the interaction between ACE2 and Spike protein (S) being …

Fabry disease is a rare X-linked inborn error of metabolism that has a high prevalence of
chronic kidney disease (CKD) and renal failure. It is due to the deficiency of the α …

Fabry disease is a rare X-linked lysosomal storage disorder that causes progressive cellular
accumulation of glycosphingolipids, leading to various end-organ manifestations such as …

Abstract Introduction: Gitelman's and Bartter's syndromes (GS/BS) are two rare genetic
tubulopathies which present with metabolic alkalosis and increased ACE2 levels. ACE2 …