[HTML][HTML] Thalamic alterations in motor neuron diseases: a systematic review of MRI findings

S Mohammadi, S Ghaderi, M Mohammadi… - Journal of Integrative …, 2024 - imrpress.com
Background: Motor neuron diseases (MNDs) are progressive neurodegenerative disorders
characterized by motor impairment and non-motor symptoms. The involvement of the …

Current challenges in primary lateral sclerosis diagnosis

M Oliveira Santos, M Swash… - Expert Review of …, 2024 - Taylor & Francis
Introduction Primary lateral sclerosis (PLS) is a rare, adult-onset and slowly progressive
motor neuron disorder whose clinical core is characterized by upper motor neuron (UMN) …

Supra-and infra-tentorial degeneration patterns in primary lateral sclerosis: a multimodal longitudinal neuroradiology study

J Kleinerova, M Tahedl, EL Tan, S Delaney… - Journal of …, 2024 - Springer
Background Primary lateral sclerosis (PLS) is traditionally solely associated with progressive
upper motor neuron dysfunction manifesting in limb spasticity, gait impairment, bulbar …

Language deficits in primary lateral sclerosis: cortical atrophy, white matter degeneration and functional disconnection between cerebral regions

EL Tan, M Tahedl, J Lope, JC Hengeveld… - Journal of …, 2024 - Springer
Background Primary lateral sclerosis (PLS) is traditionally regarded as a pure upper motor
neuron disorder, but recent cases series have highlighted cognitive deficits in executive and …

Evidence based on Mendelian randomization and colocalization analysis strengthens causal relationships between structural changes in specific brain regions and …

J Shi, Z Wang, M Yi, S Xie, X Zhang, D Tao… - Frontiers in …, 2024 - frontiersin.org
Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease
characterized by the degeneration of motor neurons in the brain and spinal cord with a poor …