Clostridium difficile (C. difficile) infection (CDI) is the most common cause of healthcare‑
associated diarrhea and among adults, the worldwide incidence rate of the infection is …

Clostridioides difficile is the leading cause of antibiotic-associated infectious diarrhea. The
development of C. difficile infection is tied to perturbations of the bacterial community in the …

Clostridioides difficile infection (CDI) is a major cause of healthcare-associated diarrhea,
despite the widespread implementation of contact precautions for patients with CDI. Here …

Prevention of Clostridium difficile infection is challenging worldwide owing to its high
morbidity and mortality rates. C. difficile is currently being classified as an urgent threat by …

Abstract The dipeptide D‐Ala‐D‐Ala is an essential component of peptidoglycan and the
target of vancomycin. Most Clostridioides difficile strains possess the vanG operon …

C. difficile infection (CDI) has an important impact on both human and animal health. The
rapid detection and monitoring of C. difficile PCR-ribotypes (RTs) cause of CDI is critical to …

Clostridioides difficile is a Gram-positive, anaerobic, and spore-forming bacterial member of
the human gut microbiome. The primary virulence factors of C. difficile are toxin A and toxin …

Clostridioides difficile (C. difficile) is a predominant nosocomial infection, and guidelines for
improving diagnosis and treatment were published in 2017. We conducted a single-center …

TcdB is an intracellular bacterial toxin indispensable to Clostridioides difficile infections. The
ability to use chondroitin sulfate proteoglycan 4 (CSPG4) as a primary cell surface receptor …

Objectives Clostridioides difficile infection (CDI) is the leading hospital-acquired infection in
North America. While previous work on fecal microbiota transplantation (FMT), a highly …