Chromatin-and nucleosome-associated features in liquid biopsy: implications for cancer biomarker discovery
L Penny, SC Main, SD De Michino… - Biochemistry and Cell …, 2024 - cdnsciencepub.com
Cell-free DNA (cfDNA) from the bloodstream has been studied for cancer biomarker
discovery, and chromatin-derived epigenetic features have come into the spotlight for their …
discovery, and chromatin-derived epigenetic features have come into the spotlight for their …
Mechanistic QSAR modeling derived virtual screening, drug repurposing, ADMET and in-vitro evaluation to identify anticancer lead as lysine-specific demethylase …
RD Jawarkar, MEA Zaki, SA Al-Hussain… - Journal of …, 2024 - Taylor & Francis
A lysine-specific demethylase is an enzyme that selectively eliminates methyl groups from
lysine residues. KDM5A, also known as JARID1A or RBP2, belongs to the KDM5 Jumonji …
lysine residues. KDM5A, also known as JARID1A or RBP2, belongs to the KDM5 Jumonji …
The Unique Role of the Second Coordination Sphere to Unlock and Control Catalysis in Nonheme Fe (II)/2-Oxoglutarate Histone Demethylase KDM2A
MG Thomas, SB Jaber Sathik Rifayee… - Inorganic …, 2024 - ACS Publications
Nonheme Fe (II) and 2-oxoglutarate (2OG)-dependent histone lysine demethylases 2A
(KDM2A) catalyze the demethylation of the mono-or dimethylated lysine 36 residue in the …
(KDM2A) catalyze the demethylation of the mono-or dimethylated lysine 36 residue in the …
Integrated virtual screening and MD simulation approaches toward discovering potential inhibitors for targeting BRPF1 bromodomain in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most aggressive and life-threatening cancers.
Although multiple treatment options are available, the prognosis of HCC patients is poor due …
Although multiple treatment options are available, the prognosis of HCC patients is poor due …
Identification of SWI/SNF Subcomplex GBAF Presence, Intra-Complex Interactions, and Transcriptional Dynamics during Early Porcine Development
S Innis, A Alpsoy, J Crodian, YC Tseng, E Dykhuizen… - Animals, 2024 - mdpi.com
Simple Summary Epigenetics is the study of heritable features known as epigenetic marks
and other mechanisms that regulate how and when gene expression happens within a cell …
and other mechanisms that regulate how and when gene expression happens within a cell …
油茶果生刺盘孢组蛋白乙酰化转移酶Rtt109 生物学功能.
王成玉， 姚权， 李河 - Mycosystema, 2024 - search.ebscohost.com
炭疽病是油茶的主要病害, 造成巨大经济损失. 果生刺盘孢是油茶炭疽病优势致病菌.
本研究旨在探讨果生刺盘孢中组蛋白乙酰化转移酶Rtt109 的生物学功能 …
本研究旨在探讨果生刺盘孢中组蛋白乙酰化转移酶Rtt109 的生物学功能 …
[HTML][HTML] H3K4 methylation regulates development, DNA repair, and virulence in Mucorales
M Osorio-Concepción, C Lax, D Lorenzo-Gutiérrez… - IMA fungus, 2024 - Springer
Mucorales are basal fungi that opportunistically cause a potentially fatal infection known as
mucormycosis (black fungus disease), which poses a significant threat to human health due …
mucormycosis (black fungus disease), which poses a significant threat to human health due …
Epigenetics of transgenerational inheritance of disease
ED Watson - Epigenetics in Human Disease, 2024 - Elsevier
Elucidating how the environment affects human health will further our understanding of
disease risk and prevention, and our potential for adaptation, such as how metabolism …
disease risk and prevention, and our potential for adaptation, such as how metabolism …
The Cooperation of Condensin, Histone Methylation, and Nuclear Lamina Tethering Maintains X Chromosome Repression after the Establishment of Dosage …
J Trombley - 2024 - deepblue.lib.umich.edu
Caenorhabditis elegans exists as two heterogametic sexes: hermaphrodites and males. The
hermaphrodites have two X chromosomes, XX, whereas the males only have one sex …
hermaphrodites have two X chromosomes, XX, whereas the males only have one sex …
[PDF][PDF] Characterization of epigenetic mechanisms involved in embryo implantation
R Shima - 2024 - pea.lib.pte.hu
1.1. Epigenetics A growing body of evidence shows that, in addition to the inherited genetic
make-up (ie genomic DNA), various environmental factors also contribute significantly to the …
make-up (ie genomic DNA), various environmental factors also contribute significantly to the …