Despite significant advances in the field of transplantation in the past two decades, current
clinically available therapeutic options for immunomodulation remain fairly limited. The …

Normothermic machine perfusion (NMP) has emerged as a promising tool for the
preservation, viability assessment, and repair of deceased-donor kidneys prior to …

At present, organ transplantation remains the most appropriate therapy for patients with end‐
stage organ failure. However, the field of organ transplantation is still facing many …

Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with the ability to communicate with other tissues and cell types over long distances. Their …

Background Acute hypoxic proximal tubule (PT) injury and subsequent maladaptive repair
present high mortality and increased risk of acute kidney injury (AKI)-chronic kidney disease …

The limited supply and rising demand for kidney transplantation has led to the use of
allografts more susceptible to ischemic reperfusion injury (IRI) and oxidative stress to …

The high prevalence and complex etiology of renal diseases already impose a heavy
disease burden on patients and society. In certain kidney diseases such as acute kidney …

The transplant community is focused on prolonging the ex vivo preservation time of kidney
grafts to allow for long-distance kidney graft transportation, assess the viability of marginal …

Актуальность. Неудовлетворенная потребность в трансплантологической помощи
диктует необходимость использования органов от субоптимальных доноров …