In vivo dose response and efficacy of the β-lactamase inhibitor, durlobactam, in combination with sulbactam against the Acinetobacter baumannii-calcoaceticus …
J O'Donnell, A Tanudra, A Chen… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Multi-drug resistant (MDR) Acinetobacter baumannii is emerging as a pathogen of
increasing prevalence and concern. Infections associated with this Gram-negative pathogen …
increasing prevalence and concern. Infections associated with this Gram-negative pathogen …
Population pharmacokinetics of antibacterial agents in the older population: a literature review
HX Liu, BH Tang, J van den Anker, GX Hao… - Expert review of …, 2024 - Taylor & Francis
Introduction Older individuals face an elevated risk of developing bacterial infections. The
optimal use of antibacterial agents in this population is challenging because of age-related …
optimal use of antibacterial agents in this population is challenging because of age-related …
First-in-human study to evaluate the safety, tolerability, and population pharmacokinetic/pharmacodynamic target attainment analysis of FL058 alone and in …
Z Huang, X Yang, Y Jin, J Yu, G Cao… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
ABSTRACT FL058 is a novel diazabicyclooctane β-lactamase inhibitor. This first-in-human
study evaluated the safety, tolerability, and population pharmacokinetic (PK) …
study evaluated the safety, tolerability, and population pharmacokinetic (PK) …
Stability of meropenem in portable elastomeric infusion devices: which protocol should be implemented in clinical practice?
B Esteban-Cartelle, DR Serrano… - Microbiology …, 2024 - Am Soc Microbiol
Meropenem has an excellent activity against gram-positive and gram-negative bacteria,
including multi-resistant microorganisms. Even though meropenem is a great candidate for …
including multi-resistant microorganisms. Even though meropenem is a great candidate for …
Kritikus állapotú, szeptikus felnőtt betegek antibiotikumkezelésének farmakokinetikai és farmakodinamikai megfontolásai
L Holub, BG Szabó, L Závorszky, R Hümpfner… - Orvosi …, 2024 - akjournals.com
A szepszis életet veszélyeztető, komplex klinikai állapot, melynek kezelése jelentős kihívást
és számottevő költségráfordítást jelent a betegellátás számára. A szepszis által előidézett …
és számottevő költségráfordítást jelent a betegellátás számára. A szepszis által előidézett …
[引用][C] Personalising antimicrobial therapy in critically ill patients using Bayesian dosing software
M Chai - 2024 - espace.library.uq.edu.au
Infections in critically ill patients are associated with significant morbidity and mortality
whereby prompt administration of antimicrobials is crucial to help optimise treatment …
whereby prompt administration of antimicrobials is crucial to help optimise treatment …