[HTML][HTML] Overcoming cold tumors: a combination strategy of immune checkpoint inhibitors
P Ouyang, L Wang, J Wu, Y Tian, C Chen, D Li… - Frontiers in …, 2024 - frontiersin.org
Immune Checkpoint Inhibitors (ICIs) therapy has advanced significantly in treating malignant
tumors, though most 'cold'tumors show no response. This resistance mainly arises from the …
tumors, though most 'cold'tumors show no response. This resistance mainly arises from the …
[HTML][HTML] Interventional radiology locoregional therapies for intrahepatic cholangiocarcinoma
G Woodhead, S Lee, L Struycken, D Goldberg… - Life, 2024 - mdpi.com
Surgical resection remains the cornerstone of curative treatment for intrahepatic
cholangiocarcinoma (iCCA), but this option is only available to a small percentage of …
cholangiocarcinoma (iCCA), but this option is only available to a small percentage of …
TLR3 activation enhances abscopal effect of radiotherapy in HCC by promoting tumor ferroptosis
L Qiu, H Ji, K Wang, W Liu, Q Huang, X Pan… - EMBO Molecular …, 2024 - embopress.org
Radiotherapy (RT) has been reported to induce abscopal effect in advanced hepatocellular
carcinoma (HCC), but such phenomenon was only observed in sporadic cases. Here, we …
carcinoma (HCC), but such phenomenon was only observed in sporadic cases. Here, we …
Radiotherapy Enhances Metastasis Through Immune Suppression by inducing PD-L1 and MDSC in distal sites
Purpose: Radiotherapy (RT) is a widely employed anticancer treatment. Emerging evidence
suggests that RT can elicit both tumor-inhibiting and tumor-promoting immune effects. The …
suggests that RT can elicit both tumor-inhibiting and tumor-promoting immune effects. The …
Fraction Dose Escalation of Hypofractionated Radiotherapy with Concurrent Chemotherapy and Subsequent Consolidation Immunotherapy in Locally Advanced Non …
R Zhou, FJ Liu, HM Zhang, DQ Wang, PX Zhang… - Clinical Cancer …, 2024 - AACR
Purpose: This phase I trial aimed to determine the maximum tolerated fraction dose (MTFD)
of hypofractionated radiotherapy (hypo-RT) combined with concurrent chemotherapy and …
of hypofractionated radiotherapy (hypo-RT) combined with concurrent chemotherapy and …
Expanding horizons in cancer therapy by immunoconjugates targeting tumor microenvironments
AS Fattahi, M Jafari, G Farahavar, SS Abolmaali… - Critical Reviews in …, 2024 - Elsevier
Immunoconjugates are promising molecules combining antibodies with different agents,
such as toxins, drugs, radionuclides, or cytokines that primarily aim to target tumor cells …
such as toxins, drugs, radionuclides, or cytokines that primarily aim to target tumor cells …
Synergistic effects of thermosensitive liposomal doxorubicin, mild hyperthermia, and radiotherapy in breast cancer management: an orthotopic mouse model study
X Wang, C Allen - Drug Delivery and Translational Research, 2024 - Springer
Liposome formulations of the cancer drug doxorubicin have been developed to address the
severe side effects that result from administration of this drug in a conventional formulation …
severe side effects that result from administration of this drug in a conventional formulation …
The efficacy and safety of neoadjuvant chemoradiotherapy combined with immunotherapy for locally advanced rectal cancer patients: a systematic review
L Yang, X Cui, F Wu, Z Chi, L Xiao, X Wang… - Frontiers in …, 2024 - frontiersin.org
Background Several studies have explored the effectiveness of PD-1/PD-L1 inhibitors
combined with neoadjuvant chemoradiotherapy (nCRT) in the treatment of locally advanced …
combined with neoadjuvant chemoradiotherapy (nCRT) in the treatment of locally advanced …
[HTML][HTML] Radiation nanomedicines for cancer treatment: a scientific journey and view of the landscape
Background Radiation nanomedicines are nanoparticles labeled with radionuclides that
emit α-or β-particles or Auger electrons for cancer treatment. We describe here our 15 years …
emit α-or β-particles or Auger electrons for cancer treatment. We describe here our 15 years …
[HTML][HTML] Genomic analysis of human brain metastases treated with stereotactic radiosurgery reveals unique signature based on treatment failure
Stereotactic radiosurgery (SRS) has been shown to be efficacious for the treatment of limited
brain metastasis (BM); however, the effects of SRS on human brain metastases have yet to …
brain metastasis (BM); however, the effects of SRS on human brain metastases have yet to …