[HTML][HTML] Research progress in brain-targeted nasal drug delivery
Q Huang, X Chen, S Yu, G Gong, H Shu - Frontiers in Aging …, 2024 - frontiersin.org
The unique anatomical and physiological connections between the nasal cavity and brain
provide a pathway for bypassing the blood–brain barrier to allow for direct brain-targeted …
provide a pathway for bypassing the blood–brain barrier to allow for direct brain-targeted …
[HTML][HTML] Challenges and prospects in geriatric epilepsy treatment: the role of the blood–brain barrier in pharmacotherapy and drug delivery
X Chen, J Luo, M Song, L Pan, Z Qu… - Frontiers in Aging …, 2024 - frontiersin.org
The blood–brain barrier (BBB) is pivotal in maintaining neuronal physiology within the brain.
This review delves into the alterations of the BBB specifically in the context of geriatric …
This review delves into the alterations of the BBB specifically in the context of geriatric …
Swimming short fibrous nasal drops achieving intraventricular administration
Adequate drug delivery across the blood–brain barrier (BBB) is a critical factor in treating
central nervous system (CNS) disorders. Inspired by swimming fish and the microstructure of …
central nervous system (CNS) disorders. Inspired by swimming fish and the microstructure of …
Bio–Nano Toolbox for Precision Alzheimer's Disease Gene Therapy
Alzheimer's disease (AD) is the most burdensome aging‐associated neurodegenerative
disorder, and its treatment encounters numerous failures during drug development …
disorder, and its treatment encounters numerous failures during drug development …
Nanocarrier Mediated Intranasal Drug Delivery Systems for the Management of Parkinsonism: A Review
A Kapoor, A Hafeez, P Kushwaha - Current Drug Delivery, 2024 - ingentaconnect.com
The transport of drugs to the brain becomes a key concern when treating disorders of the
central nervous system. Parkinsonism is one of the major concerns across the world …
central nervous system. Parkinsonism is one of the major concerns across the world …
Development of nanostructured environmentally responsive system containing hydroxypropyl methylcellulose for nose-to-brain administration of meloxicam
The intranasal administration of drugs using environmentally responsive formulations,
employing a combination of hydroxypropyl methylcellulose (HPMC) and poloxamer 407 …
employing a combination of hydroxypropyl methylcellulose (HPMC) and poloxamer 407 …
How Precise are Nanomedicines in Overcoming the Blood–Brain Barrier? A Comprehensive Review of the Literature
New nanotechnology strategies for enhancing drug delivery in brain disorders have recently
received increasing attention from drug designers. The treatment of neurological conditions …
received increasing attention from drug designers. The treatment of neurological conditions …
An ex vivo investigation on drug permeability of sheep nasal epithelial tissue membranes from the respiratory and olfactory regions
A Haasbroek-Pheiffer, A Viljoen… - Current Drug …, 2024 - ingentaconnect.com
Background: Besides systemic drug delivery, the intranasal route of administration has
shown potential for direct nose-to-brain drug delivery, which has gained popularity because …
shown potential for direct nose-to-brain drug delivery, which has gained popularity because …
Dihydroergotamine mesylate nasal spray: an acute treatment option for migraine in adults
M Silvestro, I Orologio, A Tessitore, F Trojsi… - Expert Review of …, 2024 - Taylor & Francis
Introduction Although the landscape of migraine symptomatic treatment has been enriched
by novel effective drugs, it is mandatory to critically reappraise older molecules to ascertain …
by novel effective drugs, it is mandatory to critically reappraise older molecules to ascertain …
[HTML][HTML] Nasal Delivery to the Brain: Harnessing Nanoparticles for Effective Drug Transport
The nose-to-brain drug-delivery system has emerged as a promising strategy to overcome
the challenges associated with conventional drug administration for central nervous system …
the challenges associated with conventional drug administration for central nervous system …