Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated
aldosterone production that occurs despite suppression of renin and angiotensin II, and that …

Resistant hypertension (RH) is a severe form of hypertension associated with increased
cardiovascular risk. Although true RH affects less than 10% of the patients receiving …

BACKGROUND: Primary aldosteronism, characterized by overt renin-independent
aldosterone production, is a common but underrecognized form of hypertension and …

Hypertension, a leading risk factor for cardiovascular disease, poses a significant public
health challenge globally. This article explores the multifaceted approach to hypertension …

The overactivation of the mineralocorticoid receptor (MR) promotes pathophysiological
processes related to multiple physiological systems, including the heart, vasculature …

Modulation of the renin-angiotensin-aldosterone system is a foundation of therapy for
cardiovascular and kidney diseases. Excess aldosterone plays an important role in …

Importance Primary aldosteronism (PA) is a common cause of secondary hypertension and
an independent risk factor for cardiovascular morbidity and mortality. Fewer than 2% to 4 …

Context Primary aldosteronism is a form of low-renin hypertension characterized by
dysregulated aldosterone production. Objective To investigate the contributions of renin …

Hypertension is the leading risk factor for premature death. The optimal treatment of low-
renin hypertension (LRH), present in 30% of hypertensive individuals, is not known. LRH …

The American Diabetes Association (ADA)“Standards of Care in Diabetes” includes the
ADA's current clinical practice recommendations and is intended to provide the components …