Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery

Y Hu, Z Dong, K Liu - Journal of Experimental & Clinical Cancer Research, 2024 - Springer
Signal transducer and activator of transcription 3 (STAT3) is a transcriptional factor involved
in almost all cancer hallmark features including tumor proliferation, metastasis …

Transcriptional elongation control of hypoxic response

SHAA Soliman, M Iwanaszko… - Proceedings of the …, 2024 - National Acad Sciences
The release of paused RNA polymerase II (RNAPII) from promoter-proximal regions is tightly
controlled to ensure proper regulation of gene expression. The elongation factor PTEF-b is …

HPV8-induced STAT3 activation led keratinocyte stem cell expansion in human actinic keratoses

HJ Morgan, C Olivero, BY Shorning, A Gibbs… - JCI insight, 2024 - insight.jci.org
HPV8-induced STAT3 activation led keratinocyte stem cell expansion in human actinic
keratoses Page 1 1 HPV8-induced STAT3 activation led keratinocyte stem cell expansion in 1 …