Bone morphogenetic protein signaling: the pathway and its regulation

T Akiyama, LA Raftery, KA Wharton - Genetics, 2024 - academic.oup.com
In the mid-1960s, bone morphogenetic proteins (BMPs) were first identified in the extracts of
bone to have the remarkable ability to induce heterotopic bone. When the Drosophila gene …

[HTML][HTML] The Role of TGF-β/SMAD Signaling in Hepatocellular Carcinoma: from Mechanism to Therapy and Prognosis

X Xin, X Cheng, F Zeng, Q Xu, L Hou - International Journal of …, 2024 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, with high
incidence and mortality, accounting for approximately 90% of liver cancer. The development …

[HTML][HTML] Transforming growth factor beta signaling and craniofacial development: modeling human diseases in zebrafish

SC Fox, AJ Waskiewicz - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
Humans and other jawed vertebrates rely heavily on their craniofacial skeleton for eating,
breathing, and communicating. As such, it is vital that the elements of the craniofacial …

Analysis of the roles of MAD proteins in the wing dimorphism of Nilaparvata lugens

M Tian, Z Lu, J Luo, H Han, D Wen, M Zhao… - Insect …, 2024 - Wiley Online Library
Wing dimorphism in Nilaparvata lugens is controlled by the insulin‐like growth factor 1 (IGF‐
1) signaling–Forkhead transcription factors (IIS‐FoxO) pathway. However, the role of this …

Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans demonstrates widespread interaction and a function in collagen secretion

M Vora, J Dietz, Z Wing, J Kelly Liu, C Rongo… - bioRxiv, 2024 - biorxiv.org
Smads and their transcription factor partners mediate the transcriptional responses of target
cells to secreted ligands of the Transforming Growth Factor-β (TGF-β) family, including those …

[PDF][PDF] Investigation on the role of the Transforming Growth Factor-beta pathway in a Parkinson's disease cell model

WH Chua - 2024 - elib.tiho-hannover.de
It has been a very eventful and challenging journey. Apart from the scientific challenges in
the laboratory, events like the relocation of our research group from Munich to Hannover, the …

[PDF][PDF] Caractérisation de biomarqueurs de la transition endothélio-mésenchymateuse dans la dystrophie endothéliale cornéenne de Fuchs

A Tchatchouang - 2024 - corpus.ulaval.ca
Résumé La dystrophie endothéliale cornéenne de Fuchs (FECD) est une pathologie qui
touche la couche postérieure de la cornée, l'endothélium cornéen. Ce dernier fait office de …