How multiscale curvature couples forces to cellular functions
Among the physicochemical cues in the cellular microenvironment that orchestrate cell
processes, the different levels of curvature in the extracellular matrix and intrinsic to the …
processes, the different levels of curvature in the extracellular matrix and intrinsic to the …
Stiffness anisotropy coordinates supracellular contractility driving long-range myotube-ECM alignment
The ability of cells to organize into tissues with proper structure and function requires the
effective coordination of proliferation, migration, polarization, and differentiation across …
effective coordination of proliferation, migration, polarization, and differentiation across …
Emerging role of lncRNAs as mechanical signaling molecules in mechanotransduction and their association with Hippo-YAP signaling: a review
S Lin, X He, Y Wang, Y Chen, A Lin - Journal of Zhejiang University …, 2024 - Springer
Cells within tissues are subject to various mechanical forces, including hydrostatic pressure,
shear stress, compression, and tension. These mechanical stimuli can be converted into …
shear stress, compression, and tension. These mechanical stimuli can be converted into …
[HTML][HTML] Development of Muscle Tendon Junction in vitro Using Aligned Electrospun PCL Fibres
The muscle tendon junction (MTJ) transmits the force generated by the muscle to the tendon
and ultimately to the bone. Tears and strains commonly occur at the MTJ where …
and ultimately to the bone. Tears and strains commonly occur at the MTJ where …
Aligned Nanofibers Promote Myoblast Polarization and Myogenesis through Activating Rac-Related Signaling Pathways
X Dong, S Su, Q Sun, P Wang, Q Hu… - … Biomaterials Science & …, 2024 - ACS Publications
The extracellular matrix (ECM) plays a crucial role in regulating cellular behaviors and
functions. However, the impact of ECM topography on muscle cell adhesion and …
functions. However, the impact of ECM topography on muscle cell adhesion and …
Geometry-driven migration efficiency of autonomous epithelial cell clusters
E Vercruysse, DB Brückner, M Gómez-González… - Nature Physics, 2024 - nature.com
The directed migration of epithelial cell collectives through coordinated movements plays a
crucial role in various physiological processes and is increasingly understood at the level of …
crucial role in various physiological processes and is increasingly understood at the level of …
Effect of 3D‐Printable Anisotropic Fibrous Hydrogels on Fabricating Artificial Skeletal Muscle Constructs
The use of fibrous hydrogel constructs is a promising strategy in tissue engineering because
of their ability to closely mimic the anisotropic structure of biological tissues. In skeletal …
of their ability to closely mimic the anisotropic structure of biological tissues. In skeletal …
[HTML][HTML] In vitro development of a muscle-tendon junction construct using decellularised extracellular matrix: Effect of cyclic tensile loading
N Iwasaki, M Roldo, A Karali, G Blunn - Biomaterials Advances, 2024 - Elsevier
The muscle tendon junction (MTJ) plays a crucial role in transmitting the force generated by
muscles to the tendon and then to the bone. Injuries such as tears and strains frequently …
muscles to the tendon and then to the bone. Injuries such as tears and strains frequently …
Regulation of myogenic differentiation of myoblasts by groove structure for the design of cell culture meat scaffolds
Y Chen, W Dai, W Xiong, Y Zhou, Z Chen, C Ge… - Food Bioscience, 2024 - Elsevier
As a meat substitute, cell cultured meat aims to simulate the composition of real meat to
provide nutrient substance. The myotube formation efficiency of myoblasts in vitro is the key …
provide nutrient substance. The myotube formation efficiency of myoblasts in vitro is the key …
Sensing the squeeze: nuclear mechanotransduction in health and disease
LK Srivastava, AJ Ehrlicher - Nucleus, 2024 - Taylor & Francis
The nucleus not only is a repository for DNA but also a center of cellular and nuclear
mechanotransduction. From nuclear deformation to the interplay between mechanosensing …
mechanotransduction. From nuclear deformation to the interplay between mechanosensing …