Fetal exposure to prenatal stress can have significant consequences on short-and long-term
health. Epigenetic mechanisms, especially DNA methylation (DNAm), are a possible …

To date, the treatable traits (TTs) approach has been applied in the context of managing
diagnosed diseases. TTs are clinical characteristics and risk factors that can be identified …

Background Smoking impacts DNA methylation, but data are lacking on smoking-related
differential methylation by sex or dietary intake, recent smoking cessation (< 1 year) …

The impact of tobacco exposure on health varies by race and ethnicity and is closely tied to
internal nicotine dose, a marker of carcinogen uptake. DNA methylation is strongly …

Adverse childhood experiences (ACEs) contribute to numerous negative health outcomes
across the life course and across generations. Here, we extend prior work by examining the …

Background We previously reported in the “Vitamin C to Decrease the Effects of Smoking in
Pregnancy on Infant Lung Function” randomized clinical trial (RCT) that vitamin C (500 …

Green space exposure has been associated with improved mental, physical and general
health. However, the underlying biological mechanisms remain largely unknown. The aim of …

Smoking exposure during adulthood can disrupt oocyte development in women, contributing
to infertility and possibly adverse birth outcomes. Some of these effects may be reflected in …

Epigenetic age acceleration (EAA), defined as the difference between chronological age
and epigenetically predicted age, was calculated from multiple gestational epigenetic clocks …

Prior research has identified epigenetic predictors of attention problems in school-aged
children but has not yet investigated these in young children, or children at elevated risk of …