Relevance of Multiple Sclerosis Severity Genotype in Predicting Disease Course: A Real‐World Cohort
KL Kreft, E Uzochukwu, S Loveless, M Willis… - Annals of …, 2024 - Wiley Online Library
Objective Currently, 233 genetic loci are known to be associated with susceptibility to
multiple sclerosis (MS). Two independent pivotal severity genome‐wide association studies …
multiple sclerosis (MS). Two independent pivotal severity genome‐wide association studies …
Spontaneous human CD8 T cell and autoimmune encephalomyelitis-induced CD4/CD8 T cell lesions in the brain and spinal cord of HLA-DRB1* 15-positive multiple …
I Papazian, M Kourouvani, A Dagkonaki, V Gouzouasis… - eLife, 2024 - elifesciences.org
Autoimmune diseases of the central nervous system (CNS) such as multiple sclerosis (MS)
are only partially represented in current experimental models and the development of …
are only partially represented in current experimental models and the development of …
Genetic contribution to medium-term disease activity in multiple sclerosis
E Mascia, V Nale, L Ferrè, M Sorosina, F Clarelli… - Molecular …, 2024 - Springer
Multiple sclerosis (MS) is a complex disorder characterized by high heterogeneity in terms of
phenotypic expression, prognosis and treatment response. In the present study, we aimed to …
phenotypic expression, prognosis and treatment response. In the present study, we aimed to …
Adaptive and Innate Immunity Are Key Drivers of Age at Onset of Multiple Sclerosis
Background and Objectives Multiple sclerosis (MS) age at onset (AAO) is a clinical predictor
of long-term disease outcomes, independent of disease duration. Little is known about the …
of long-term disease outcomes, independent of disease duration. Little is known about the …
Pediatric multiple sclerosis and acute disseminated encephalomyelitis
KA O'Neill, C Fernandez-Carbonell… - The Rose and Mackay …, 2024 - Elsevier
Multiple sclerosis (MS), commonly a disease of young adulthood, occurs in children and
adolescents at an estimated 2%–5% frequency in the MS population. Pediatric MS refers to …
adolescents at an estimated 2%–5% frequency in the MS population. Pediatric MS refers to …
Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden
H Gauffin, I Boström, SG Berntsson… - Journal of Clinical …, 2024 - mdpi.com
(1) Background: In the context of the H1N1 pandemic and the Pandemrix vaccination
campaign, an increased number of narcolepsy cases were noted in several countries. In …
campaign, an increased number of narcolepsy cases were noted in several countries. In …
Neuropathology of Neurological Disorders
Neuropathology delineates the examination of cells and tissues, to assimilate the structure
and function of the neurological system as well as the diagnosis and pathology of diseases …
and function of the neurological system as well as the diagnosis and pathology of diseases …
Metabolic control of neural stem cell function in a patient-derived model of multiple sclerosis
RB Ionescu - 2024 - repository.cam.ac.uk
Multiple sclerosis (MS), the most prevalent inflammatory autoimmune disorder affecting the
central nervous system (CNS), results in the deterioration of myelin sheaths and neuronal …
central nervous system (CNS), results in the deterioration of myelin sheaths and neuronal …