Discovery, structure, mechanisms, and evolution of protein-only RNase P enzymes
W Rossmanith, P Giegé, RK Hartmann - Journal of Biological Chemistry, 2024 - ASBMB
The endoribonuclease RNase P is responsible for tRNA 5′ maturation in all domains of life.
A unique feature of RNase P is the variety of enzyme architectures, ranging from dual-to …
A unique feature of RNase P is the variety of enzyme architectures, ranging from dual-to …
The protein‐only RNase Ps, endonucleases that cleave pre‐tRNA: Biological relevance, molecular architectures, substrate recognition and specificity, and protein …
CA Wilhelm, K Kaitany, A Kelly… - Wiley …, 2024 - Wiley Online Library
Abstract Protein‐only RNase P (PRORP) is an essential enzyme responsible for the 5′
maturation of precursor tRNAs (pre‐tRNAs). PRORPs are classified into three categories …
maturation of precursor tRNAs (pre‐tRNAs). PRORPs are classified into three categories …
Multiple structural flavors of RNase P in precursor tRNA processing
S Sridhara - Wiley Interdisciplinary Reviews: RNA, 2024 - Wiley Online Library
The precursor transfer RNAs (pre‐tRNAs) require extensive processing to generate mature
tRNAs possessing proper fold, structural stability, and functionality required to sustain …
tRNAs possessing proper fold, structural stability, and functionality required to sustain …
A minimal RNA substrate with dual fluorescent probes enables rapid kinetics and provides insight into bacterial RNase P active site interactions
Bacterial ribonuclease P (RNase P) is a tRNA processing endonuclease that occurs
primarily as a ribonucleoprotein with a catalytic RNA subunit (P RNA). As one of the first …
primarily as a ribonucleoprotein with a catalytic RNA subunit (P RNA). As one of the first …