Quantifying cell-state densities in single-cell phenotypic landscapes using Mellon

DJ Otto, C Jordan, B Dury, C Dien, M Setty - Nature Methods, 2024 - nature.com
Cell-state density characterizes the distribution of cells along phenotypic landscapes and is
crucial for unraveling the mechanisms that drive diverse biological processes. Here, we …

Genome‐wide DNase I‐hypersensitive site assay reveals distinct genomic distributions and functional features of open chromatin in autopolyploid sugarcane

G Yu, B Sun, Z Zhu, EM Mehareb, A Teng… - The Plant …, 2024 - Wiley Online Library
The characterization of cis‐regulatory DNA elements (CREs) is essential for deciphering the
regulation of gene expression in eukaryotes. Although there have been endeavors to …

Multi-modal Transfer Learning between Biological Foundation Models

JJ Garau-Luis, P Bordes, L Gonzalez, M Roller… - arXiv preprint arXiv …, 2024 - arxiv.org
Biological sequences encode fundamental instructions for the building blocks of life, in the
form of DNA, RNA, and proteins. Modeling these sequences is key to understand disease …

[引用][C] Investigating the cis-regulatory mechanisms underlying neuronal imprinted expression

D Loftus - 2024