Biomaterial choice is an essential step during the development tissue engineering and
regenerative medicine (TERM) applications. The selected biomaterial must present …

Cardiac aging, particularly cardiac cell senescence, is a natural process that occurs as we
age. Heart function gradually declines in old age, leading to continuous heart failure, even in …

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease resulting in irreversible scarring
within the lungs. However, the lack of biomarkers that enable real-time assessment of …

Fibronectin (FN) is a critical component of extracellular matrix (ECM) contributing to various
physiological processes, including tissue repair and immune response regulation. FN …

Background Diabetes-induced cardiac fibrosis is one of the main mechanisms of diabetic
cardiomyopathy. As a common histone methyltransferase, enhancer of zeste homolog 2 …

Intervertebral disc degeneration involves the breakdown of the discs of the spine due to
genetics, aging, or faulty mechanical loading. As part of the progression of the disease …

The discovery of extracellular vesicles (EVs) as efficient exogenous biotransporters of
therapeutic agents into cells across biological membranes is an exciting emerging field …

Shenfu injection (SFI), composed of ginseng and aconite, is a Chinese patent developed
from the classic traditional prescription Shenfu Decoction created more than 700 years ago …

Aim Cardiac fibrosis is characterized by excessive accumulation of fibrous tissue,
particularly collagens, in the myocardium. Accumulated fibrous tissue renders myocardium …

Elucidating how cell populations promote onset and progression of intervertebral disc
degeneration (IDD) has the potential to enable more precise therapeutic targeting of cells …