Granzyme K–and amphiregulin-expressing cytotoxic T cells and activated extrafollicular B cells are potential drivers of IgG4-related disease
R Koga, T Maehara, R Aoyagi, R Munemura… - Journal of Allergy and …, 2024 - Elsevier
Background IgG4-related disease (IgG4-RD), an example of a type I immune disease, is an
immune-mediated fibrotic disorder characterized by dysregulated resolution of severe …
immune-mediated fibrotic disorder characterized by dysregulated resolution of severe …
Single-cell transcriptomics reveals granzyme K–expressing cytotoxic Tfh cells in tertiary lymphoid structures in IgG4-RD
R Aoyagi, T Maehara, R Koga, R Munemura… - Journal of Allergy and …, 2024 - Elsevier
Background Germinal center (GC) responses controlled by T follicular helper (Tfh) and T
follicular regulatory (Tfr) cells are crucial for the generation of high-affinity antibodies …
follicular regulatory (Tfr) cells are crucial for the generation of high-affinity antibodies …