Molecular hybridization represents a new approach in drug discovery in which specific
chromophores are strategically combined to create novel drugs with enhanced therapeutic …

The COVID-19 pandemic that started in 2019 and resulted in significant morbidity and
mortality continues to be a significant global health challenge, characterized by …

In our quest to discover effective inhibitors against severe acute respiratory syndrome
coronavirus 2 helicase, a diverse set of more than 300 naturally occurring antiviral …

Flavonoids are vital candidates to fight against a wide range of pathogenic microbial
infections. Due to their therapeutic potential, many flavonoids from the herbs of traditional …

Chalcones have been utilized for centuries as foods and medicines across various cultures
and traditions worldwide. This paper concisely overviews their biosynthesis as specialized …

ABSTRACT Introduction Highly pathogenic coronaviruses (CoVs), such as severe acute
respiratory syndrome CoV (SARS-CoV), Middle East respiratory syndrome CoV (MERS …

COVID-19 continues to claim victims in the world, especially among elderly subjects and
people suffering from chronic-degenerative pathologies, like cardiovascular diseases …

Statins are cholesterol-lowering drugs with a mechanism of inhibiting 3-hydroxy-3-
methylglutaryl-CoA reductase, but long-term use can cause side effects. An example of a …

Acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the recent pandemic
and worldwide outbreak of respiratory disease. Since there are no known specific drugs for …

Chalcones, a class of secondary metabolites within the flavonoid family, are characterized
by a distinct C6-C3-C6 structure. They are prevalent in both edible and medicinal plants and …