Dysregulation of sphingolipid metabolism in pain

J Wang, G Zheng, L Wang, L Meng, J Ren… - Frontiers in …, 2024 - frontiersin.org
Pain is a clinical condition that is currently of great concern and is often caused by tissue or
nerve damage or occurs as a concomitant symptom of a variety of diseases such as cancer …

Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum

Y Song, Z Zhao, L Xu, P Huang, J Gao, J Li, X Wang… - Developmental Cell, 2024 - cell.com
The ability of cells to perceive and respond to mechanical cues is essential for numerous
biological activities. Emerging evidence indicates important contributions of organelles to …

A small-molecule probe to decipher stress-induced ER microenvironments and ER-Golgi communication

T Dutta, B Chakraborty, A Nigam, S Minocha… - Journal of Materials …, 2024 - pubs.rsc.org
Cellular stress is a crucial factor in regulating and maintaining both organismal and
microenvironmental homeostasis. It induces a response that also affects the micropolarity of …

Visualization of ER-to-Golgi trafficking of procollagen X

Y Ximin, H Hashimoto, I Wada… - Cell Structure and …, 2024 - jstage.jst.go.jp
Collagen is the most abundant protein in the extracellular matrix of animals, and 28 types of
collagen have been reported in humans. We previously analyzed the endoplasmic reticulum …