[HTML][HTML] Accuracy of HPV E6/E7 oncoprotein tests to detect high-grade cervical lesions: a systematic literature review and meta-analysis

L Downham, I Jaafar, ML Rol, V Nyawira Nyaga… - British Journal of …, 2024 - nature.com
Background Cervical carcinogenesis is mediated by the HPV-E6 and E7 oncoproteins,
considered as biomarkers usable in managing screen-positive women. Methods We …

Human malignancies associated with persistent HPV infection

AA McBride - The Oncologist, 2024 - academic.oup.com
Human papillomavirus (HPV)-associated malignancies account for~ 5% of human cancers
worldwide. Thirteen, or more, HPV types are oncogenic, but infection with these viruses is …

Insights into the mechanisms and structure of breakage-fusion-bridge cycles in cervical cancer using long-read sequencing

I Rodriguez, NM Rossi, AG Keskus, Y Xie… - The American Journal of …, 2024 - cell.com
Cervical cancer is caused by human papillomavirus (HPV) infection, has few approved
targeted therapeutics, and is the most common cause of cancer death in low-resource …

Testing for viral DNA integration among HPV‐positive women to detect cervical precancer: An observational cohort study

T Hu, K Li, L He, F Huang, F Yang… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Objective Human papillomavirus (HPV) integration is a crucial genetic step in cervical
carcinogenesis. This study aimed to evaluate the performance of an HPV integration test for …

[HTML][HTML] PCDHGB7 hypermethylation-based Cervical cancer Methylation (CerMe) detection for the triage of high-risk human papillomavirus-positive women: a …

D Cao, Z Yang, S Dong, Y Li, Z Mao, Q Lu, P Xu… - BMC medicine, 2024 - Springer
Background Implementation of high-risk human papillomavirus (hrHPV) screening has
greatly reduced the incidence and mortality of cervical cancer. However, a triage strategy …

[HTML][HTML] STINGing Defenses: Unmasking the Mechanisms of DNA Oncovirus-Mediated Immune Escape

MF Martínez-López, C Muslin, NC Kyriakidis - Viruses, 2024 - mdpi.com
DNA oncoviruses represent an intriguing subject due to their involvement in oncogenesis.
These viruses have evolved mechanisms to manipulate the host immune response …

miR‐129‐5p inhibits anchorage‐independent growth through silencing of ACTN1 and the ELK4/c‐FOS axis in HPV‐transformed keratinocytes

A Huseinovic, M Xu, A Jaspers, B Bais… - Journal of Medical …, 2024 - Wiley Online Library
A persistent infection with human papillomavirus (HPV) can induce precancerous lesions of
the cervix that may ultimately develop into cancer. Cervical cancer development has been …

Addressing the burden of cervical cancer for Indigenous women in Latin America and the Caribbean: a call for action

C Muslin - Frontiers in Public Health, 2024 - frontiersin.org
Cervical cancer, primarily caused by human papillomavirus (HPV) infection, poses a
significant global health challenge. Due to higher levels of poverty and health inequities …

[HTML][HTML] Emerging trends and hotspots in cervical intraepithelial neoplasia research from 2013 to 2023: A bibliometric analysis

L Wang, B Sun, J Xu, D Cao, Y Chen, Y Xu, D Wu - Heliyon, 2024 - cell.com
Background Cervical intraepithelial neoplasia (CIN) encompasses a range of cervical
lesions that are closely linked to cervical invasive carcinoma. Early detection and timely …

[HTML][HTML] Prevalence and genotype distribution of HPV infections among women in Chengdu, China

J Zhang, T Zha, X Wang, W He - Virology Journal, 2024 - Springer
Background Human papilloma virus (HPV) infection among female is the cause of cervical
cancer and genital warts. In China, the HPV vaccination rate and the target population …