[HTML][HTML] The neurobiology of SARS-CoV-2 infection

J Meinhardt, S Streit, C Dittmayer, RV Manitius… - Nature Reviews …, 2024 - nature.com
Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated
55–60% of those infected developing COVID-19. Since the beginning of the pandemic in …

[HTML][HTML] Neutrophils in physiology and pathology

A Aroca-Crevillén, T Vicanolo, S Ovadia… - Annual Review of …, 2024 - annualreviews.org
Infections, cardiovascular disease, and cancer are major causes of disease and death
worldwide. Neutrophils are inescapably associated with each of these health concerns, by …

[HTML][HTML] Dictionary learning for integrative, multimodal and scalable single-cell analysis

Y Hao, T Stuart, MH Kowalski, S Choudhary… - Nature …, 2024 - nature.com
Mapping single-cell sequencing profiles to comprehensive reference datasets provides a
powerful alternative to unsupervised analysis. However, most reference datasets are …

[HTML][HTML] Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early-and late-phase COVID-19

J Radke, J Meinhardt, T Aschman, RL Chua… - Nature …, 2024 - nature.com
Neurological symptoms, including cognitive impairment and fatigue, can occur in both the
acute infection phase of coronavirus disease 2019 (COVID-19) and at later stages, yet the …

[HTML][HTML] Innate immunity in protection and pathogenesis during coronavirus infections and COVID-19

RKS Malireddi, BR Sharma… - Annual Review of …, 2024 - annualreviews.org
The COVID-19 pandemic was caused by the recently emerged β-coronavirus SARS-CoV-2.
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …

SingPro: a knowledge base providing single-cell proteomic data

X Lian, Y Zhang, Y Zhou, X Sun, S Huang… - Nucleic Acids …, 2024 - academic.oup.com
Single-cell proteomics (SCP) has emerged as a powerful tool for detecting cellular
heterogeneity, offering unprecedented insights into biological mechanisms that are masked …

[HTML][HTML] Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19

AL Hanson, MP Mulè, H Ruffieux, F Mescia… - Nature …, 2024 - nature.com
Persistent symptoms following SARS-CoV-2 infection are increasingly reported, although
the drivers of post-acute sequelae (PASC) of COVID-19 are unclear. Here we assessed 214 …

Adaptive immune cells are necessary for SARS-CoV-2–induced pathology

B Imbiakha, JM Sahler, DW Buchholz, S Ezzatpour… - Science …, 2024 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the ongoing
global pandemic associated with morbidity and mortality in humans. Although disease …

[HTML][HTML] Community-acquired bacterial coinfections and COVID-19

MJ Patton, A Gaggar, M Might… - Physiological …, 2024 - journals.physiology.org
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the 29
causative pathogen of Coronavirus disease 2019 (COVID-19), has resulted in over 650 30 …

[HTML][HTML] Single-cell atlas of the liver myeloid compartment before and after cure of chronic viral hepatitis

A Cui, B Li, MS Wallace, ALK Gonye, C Oetheimer… - Journal of …, 2024 - Elsevier
Background & Aims Chronic viral infections present serious public health challenges;
however, direct-acting antivirals (DAAs) are now able to cure nearly all patients infected with …