[HTML][HTML] Orthoflaviviral Inhibitors in Clinical Trials, Preclinical In Vivo Efficacy Targeting NS2B-NS3 and Cellular Antiviral Activity via Competitive Protease Inhibition
L Cavina, MJ Bouma, D Gironés, MC Feiters - Molecules, 2024 - mdpi.com
Orthoflaviviruses, including zika (ZIKV), West Nile (WNV), and dengue (DENV) virus, induce
severely debilitating infections and contribute significantly to the global disease burden, yet …
severely debilitating infections and contribute significantly to the global disease burden, yet …
Hydroxychloroquine interaction with phosphoinositide 3-kinase modulates prostate cancer growth in bone microenvironment: In vitro and molecular dynamics based …
Patients with advanced prostate cancer (PCa) are more likely to develop bone metastases.
Tumor cells thrive in the bone microenvironment, interacting with osteoblasts and …
Tumor cells thrive in the bone microenvironment, interacting with osteoblasts and …
Impairment of substrate-mediated mitochondrial respiration in cardiac cells by chloroquine
S Ashok, SR Raji, S Manjunatha, G Srinivas - Molecular and Cellular …, 2024 - Springer
Chloroquine (CQ) has a long clinical history as an anti-malarial agent and also being used
for the treatment of other infections and autoimmune diseases. Recently, this lysosomotropic …
for the treatment of other infections and autoimmune diseases. Recently, this lysosomotropic …