Molecular mechanisms of circular RNA translation
HJ Hwang, YK Kim - Experimental & Molecular Medicine, 2024 - nature.com
Circular RNAs (circRNAs) are covalently closed single-stranded RNAs without a 5′ cap
structure and a 3′ poly (A) tail typically present in linear mRNAs of eukaryotic cells …
structure and a 3′ poly (A) tail typically present in linear mRNAs of eukaryotic cells …
Deciphering the intricate hierarchical gene regulatory network: Unraveling multi-level regulation and modifications driving secondary cell wall formation
Z Wei, H Wei - Horticulture Research, 2024 - academic.oup.com
Wood quality is predominantly determined by the amount and the composition of secondary
cell walls (SCWs). Consequently, unraveling the molecular regulatory mechanisms …
cell walls (SCWs). Consequently, unraveling the molecular regulatory mechanisms …
A circular RNA-gawky-chromatin regulatory axis modulates stress-induced transcription
In response to heavy metal stress, the RNA-binding protein (RBP) gawky translocates into
the nucleus and acts as a chromatin-interacting factor to activate the transcription of many …
the nucleus and acts as a chromatin-interacting factor to activate the transcription of many …
Bi-SGTAR: A simple yet efficient model for circRNA-disease association prediction based on known association pair only
S Li, Q Chen, Z Liu, S Pan, S Zhang - Knowledge-Based Systems, 2024 - Elsevier
Identifying circRNA (circular RNA) associated with diseases holds promise as diagnostic
and prognostic biomarkers, offering potential avenues for novel therapeutics. Several …
and prognostic biomarkers, offering potential avenues for novel therapeutics. Several …
Circular RNAs in the KRAS pathway: Emerging players in cancer progression
Circular RNAs (circRNAs) have been recognized as key components in the intricate
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …
Identification and characterization of circular RNAs involved in the fertility stability of cotton CMS-D2 restorer line under heat stress
R Wang, M Zhang, H Wang, L Chen, X Zhang, L Guo… - BMC Plant …, 2024 - Springer
Background As a vital type of noncoding RNAs, circular RNAs (circRNAs) play important
roles in plant growth and development and stress response. However, little is known about …
roles in plant growth and development and stress response. However, little is known about …
EIF4A3-negatively driven circular RNA β-catenin (circβ-catenin) promotes colorectal cancer progression via miR-197-3p/CTNND1 regulatory axis
LQ Deng, CJ Shi, ST Zhou, WQ Zeng, YF Xian… - British Journal of …, 2024 - nature.com
Background Circβ-catenin, our first reported circRNA, has been reported to mediate
tumorigenesis in various cancers. However, its biological functions and underlying …
tumorigenesis in various cancers. However, its biological functions and underlying …
Current RNA strategies in treating cardiovascular diseases
Cardiovascular disease (CVD) continues to impose a significant global health burden,
necessitating the exploration of innovative treatment strategies. Ribonucleic acid (RNA) …
necessitating the exploration of innovative treatment strategies. Ribonucleic acid (RNA) …
[HTML][HTML] New insights into the potential of exosomal circular RNAs in mediating cancer chemotherapy resistance and their clinical applications
Q Li, Y Zhang, P Jin, Y Chen, C Zhang, X Geng… - Biomedicine & …, 2024 - Elsevier
Chemotherapy resistance typically leads to tumour recurrence and is a major obstacle to
cancer treatment. Increasing numbers of circular RNAs (circRNAs) have been confirmed to …
cancer treatment. Increasing numbers of circular RNAs (circRNAs) have been confirmed to …
Exploring the interplay between PARP1 and circRNA biogenesis and function
H Dhahri, YN Fondufe‐Mittendorf - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Abstract PARP1 (poly‐ADP‐ribose polymerase 1) is a multidomain protein with a flexible
and self‐folding structure that allows it to interact with a wide range of biomolecules …
and self‐folding structure that allows it to interact with a wide range of biomolecules …