Benzothiazole‐based apoptosis inducers: A comprehensive overview and future prospective
Cancer has become a major concern in healthcare globally, and over time, incidences and
prevalence of cancer are increasing. To counter this, a lot of anticancer drugs are approved …
prevalence of cancer are increasing. To counter this, a lot of anticancer drugs are approved …
FAK inhibitors in cancer, a patent review-an update on progress
YX Ye, YY Cao, LS Xu, HC Wang, XH Liu… - Expert Opinion on …, 2024 - Taylor & Francis
Focal adhesion kinase (FAK) is a cytoplasmic non-receptor tyrosine kinase over-expressed
in various malignancies which is related to various cellular functions such as adhesion …
in various malignancies which is related to various cellular functions such as adhesion …
Exploring the effect of substituents on the supramolecular assemblies built by non-covalent interactions in three closely related 1, 3, 4-oxadiazole-2 (3H)-thione …
LH Al-Wahaibi, V Krishnan, HM Hassan… - Journal of Molecular …, 2024 - Elsevier
Abstract Three closely related 1, 3, 4-oxadiazole-2 (3H)-thione N-Mannich bases were
synthesized and characterized by spectroscopic and single crystal X-ray diffraction methods …
synthesized and characterized by spectroscopic and single crystal X-ray diffraction methods …
[HTML][HTML] Synthesis and biological evaluation of 1, 3, 4-oxadiazole Linked Thiazole-Isoxazole-Pyridines as anticancer agents
KR Gankidi, S Shivakumara, KR Reddy… - Results in …, 2024 - Elsevier
Abstract A new library of 1, 3, 4-oxadiazole moiety incorporated thiazol-isoxazol-pyridine
derivatives (9a-j) have been synthesized and assessed for preliminary anticancer …
derivatives (9a-j) have been synthesized and assessed for preliminary anticancer …
Novel 1, 3, 4-oxadiazole-2-thiol derivatives: Unlocking the therapeutic potential as anti-inflammatory and anticancer agents
AC Kumar, J Rangaswamy, PM BharathKumar… - Journal of Molecular …, 2024 - Elsevier
A series of novel substituted 5-phenyl-methyl (Z)-2-(1-amino-2-((1, 3, 4-oxadiazol-2-yl) thio)
ethylidene) hydrazine-1-carboxylate scaffolds 4 (am) have been synthesized to assess their …
ethylidene) hydrazine-1-carboxylate scaffolds 4 (am) have been synthesized to assess their …
Design, Synthesis, in Vitro, and in Silico Evaluations of 1,3,4‐Oxadiazole Derivatives Linked to the Pyrrolo[2,3‐d]pyrimidine Moieties as Potent Antimicrobial Targets
J Lal Patel, N Kumar Sureddy, M Boddupalli… - …, 2024 - Wiley Online Library
Oxadiazole and its derivatives are well known assorted motif in drug design and
development. The development of bacterial infection drug resistance serves as justification …
development. The development of bacterial infection drug resistance serves as justification …
Synthesis of novel pyrido[3,4‐d]pyrimidine‐thiazolidione‐1,2,4‐oxadiazoles as potent EGFR targeting anticancer agents
BD Varaprasadu, SB Haridasyam… - Journal of Heterocyclic … - Wiley Online Library
In this study, we designed and synthesized a number of novel pyrido [3, 4‐d] pyrimidine‐
thiazolidine‐1, 2, 4‐oxadiazole derivatives and investigated them in vitro for their inhibitory …
thiazolidine‐1, 2, 4‐oxadiazole derivatives and investigated them in vitro for their inhibitory …